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在欧盟,谁接受酒精使用障碍的治疗?初级和专门医疗保健中的横断面代表性研究。

Who receives treatment for alcohol use disorders in the European Union? A cross-sectional representative study in primary and specialized health care.

机构信息

Centre for Addiction and Mental Health, 33, Russell Street, Toronto, ON M5S 2S1, Canada; Addiction Policy, Dalla Lana School of Public Health, University of Toronto, 155, College Street, 6th floor, Toronto, ON M5T 3M7, Canada; Institute of Medical Science, University of Toronto, Faculty of Medicine, Medical Sciences Building, 1, King's College Circle, Room 2374, Toronto, ON M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250, College Street, 8th floor, Toronto, ON M5T 1R8, Canada; Institute of Clinical Psychology and Psychotherapy & Centre of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universität Dresden, Chemnitzer Str. 46, 01187 Dresden, Germany.

Institute of Clinical Psychology and Psychotherapy & Centre of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universität Dresden, Chemnitzer Str. 46, 01187 Dresden, Germany.

出版信息

Eur Psychiatry. 2015 Nov;30(8):885-93. doi: 10.1016/j.eurpsy.2015.07.012. Epub 2015 Oct 5.

Abstract

BACKGROUND

Alcohol use disorders (AUDs) are highly prevalent in Europe, but only a minority of those affected receive treatment. It is therefore important to identify factors that predict treatment in order to reframe strategies aimed at improving treatment rates.

METHODS

Representative cross-sectional study with patients aged 18-64 from primary health care (PC, six European countries, n=8476, data collection 01/13-01/14) and from specialized health care (SC, eight European countries, n=1762, data collection 01/13-03/14). For descriptive purposes, six groups were distinguished, based on type of DSM-IV AUD and treatment setting. Treatment status (yes/no) for any treatment (model 1), and for SC treatment (model 2) were main outcome measures in logistic regression models.

RESULTS

AUDs were prevalent in PC (12-month prevalence: 11.8%, 95% confidence interval (CI): 11.2-12.5%), with 17.6% receiving current treatment (95%CI: 15.3-19.9%). There were clear differences between the six groups regarding key variables from all five predictor domains. Prediction of any treatment (model 1) or SC treatment (model 2) was successful with high overall accuracy (both models: 95%), sufficient sensitivity (model 1: 79%/model 2: 76%) and high specificity (both models: 98%). The most predictive single variables were daily drinking level, anxiety, severity of mental distress, and number of inpatient nights during the last 6 months.

CONCLUSIONS

Variables from four domains were highly predictive in identifying treatment for AUD, with SC treatment groups showing very high levels of social disintegration, drinking, comorbidity and functional losses. Earlier intervention and formal treatment for AUD in PC should be implemented to reduce these high levels of adverse outcomes.

摘要

背景

在欧洲,酒精使用障碍(AUD)的患病率很高,但只有少数受影响的人接受治疗。因此,确定预测治疗的因素对于重新制定旨在提高治疗率的策略非常重要。

方法

这是一项具有代表性的横断面研究,纳入了来自初级保健(PC,六个欧洲国家,n=8476,数据收集时间为 2013 年 1 月 13 日至 2014 年 1 月 14 日)和专科保健(SC,八个欧洲国家,n=1762,数据收集时间为 2013 年 1 月 13 日至 2014 年 3 月 14 日)的 18-64 岁患者。根据 DSM-IV AUD 类型和治疗环境,将患者分为六组。任何治疗(模型 1)和 SC 治疗(模型 2)的治疗状况(是/否)是主要的二分类逻辑回归模型的因变量。

结果

PC 中 AUD 的患病率较高(12 个月患病率:11.8%,95%置信区间(CI):11.2-12.5%),有 17.6%的患者正在接受当前治疗(95%CI:15.3-19.9%)。在五个预测因素领域的所有关键变量方面,六个组之间存在明显差异。任何治疗(模型 1)或 SC 治疗(模型 2)的预测都具有很高的整体准确性(两个模型:95%)、足够的敏感性(模型 1:79%/模型 2:76%)和高特异性(两个模型:98%)。最具预测性的单一变量是每日饮酒量、焦虑、精神困扰严重程度和过去 6 个月内的住院夜数。

结论

来自四个领域的变量在识别 AUD 治疗方面具有高度预测性,SC 治疗组表现出极高的社会解体、饮酒、合并症和功能丧失水平。应在 PC 中实施 AUD 的早期干预和正规治疗,以降低这些不良后果的高发生率。

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