Fan W F, Yu S R, Cosgriff T M
Department of Microbiology, Third Military Medical College, Chongqing, Sichuan, People's Republic of China.
Rev Infect Dis. 1989 May-Jun;11 Suppl 4:S847-53. doi: 10.1093/clinids/11.supplement_4.s847.
In 1978, dengue was reported in China for the first time in 32 years. Since then, epidemics involving hundreds of thousands of people have occurred in Guangdong and Guangxi provinces and on Hainan Island. These epidemics were caused by all four types of dengue virus. Aedes aegypti was the vector in coastal areas, while Aedes albopictus was the vector in inland regions. During these epidemics, case rates were very high (greater than 50%) in some areas. Case-fatality rates were generally less than 0.1% except during the 1986 outbreak on Hainan Island, when the rate was 0.25%. Hemorrhagic disease occurred in both children and adults. On Hainan Island, hemorrhagic disease was more than three times as common in the 1986 outbreak as in the 1980 outbreak; the 1980 outbreak was caused by dengue virus type 3 and the 1986 outbreak by dengue virus type 2. The weight of the evidence suggests that the reemergence of dengue in China resulted from the introduction of the infection by travelers and refugees from areas of Asia where dengue is endemic.
1978年，中国时隔32年首次报告登革热疫情。此后，广东省、广西壮族自治区及海南岛爆发了涉及数十万人的疫情。这些疫情由所有四种登革热病毒引起。埃及伊蚊是沿海地区的传播媒介，而白纹伊蚊是内陆地区的传播媒介。在这些疫情期间，一些地区的发病率非常高（超过50%）。除1986年海南岛疫情期间病死率为0.25%外，病死率一般低于0.1%。出血性疾病在儿童和成人中均有发生。在海南岛，1986年疫情中出血性疾病的发病率是1980年疫情的三倍多；1980年疫情由3型登革热病毒引起，1986年疫情由2型登革热病毒引起。大量证据表明，中国登革热疫情的再次出现是由来自登革热流行的亚洲地区的旅行者和难民传入感染所致。
