二甲胺作为由二甲基甲酰胺（DMF）原位生成的关键中间体用于硫代酰胺的合成。

Dimethylamine as the key intermediate generated in situ from dimethylformamide (DMF) for the synthesis of thioamides.

作者信息

Liu Weibing, Chen Cui, Liu Hailing

机构信息

College of Chemical Engineering, Guangdong University of Petrochemical Technology, 2 Guandu Road, Maoming 525000, P. R. China, ; Tel: +86-668-2923956.

College Analytical and Testing Centre, Beijing Normal University, No. 19, Xinjiekouwai St., Haidian District, Beijing 100875, P. R. China; Tel: +86-15010928428.

出版信息

Beilstein J Org Chem. 2015 Sep 23;11:1721-6. doi: 10.3762/bjoc.11.187. eCollection 2015.

DOI:10.3762/bjoc.11.187

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4660898/

Abstract

An improved and efficient method for the synthesis of thioamides is presented. For this transformation, dimethylamine as the key intermediate is generated in situ from dimethylformamide (DMF). All the tested substrates produced the desired products with excellent isolated yields.

摘要

本文提出了一种改进的、高效的硫代酰胺合成方法。对于这种转化，二甲胺作为关键中间体由二甲基甲酰胺（DMF）原位生成。所有测试的底物都以优异的分离产率得到了所需产物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da73/4660898/7cdfd30f254a/Beilstein_J_Org_Chem-11-1721-g002.jpg

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