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表现为鼻前庭急性炎症的鼻NK/T细胞淋巴瘤

Nasal NK/T-cell Lymphoma Presenting as Acute Inflammation of Nasal Vestibule.

作者信息

Vasiwala Rafiqahmed, Mohamad Irfan, Venkateswaran Sunil Pazhayanur, Hamzah Syed Zaifullah

机构信息

1Department of Otorhinolaryngology, International Medical University, Clinical Campus Jalan Rasah,, 70300 Seremban, Negeri Sembilan Malaysia.

2Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, University Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan Malaysia.

出版信息

Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1986-1989. doi: 10.1007/s12070-018-1402-8. Epub 2018 May 19.

Abstract

Extra nodal nasal NK/T cell lymphoma is relatively a rare type of non-Hodgkin lymphoma. Variable clinical presentation with rapidly progressive necrosis of the cartilaginous and bony wall of the nose and upper respiratory passages leads to delayed diagnosis and treatment. A 43-years-old patient presented with right nasal pain and furuncle-like swelling. The swelling progressed rapidly to cellulitis to the face up to the right eye. Within 2 months, it had advanced to necrosis of the lateral vestibular cartilage, medial maxillary wall, turbinate and nasal septal cartilage. Biopsy reported as non-Hodgkin diffuse T cell (angiocentric T cell) lymphoma.

摘要

结外鼻型NK/T细胞淋巴瘤是一种相对罕见的非霍奇金淋巴瘤。临床表现多样,鼻和上呼吸道软骨及骨壁迅速进行性坏死,导致诊断和治疗延迟。一名43岁患者出现右侧鼻痛和疖样肿胀。肿胀迅速发展为面部蜂窝织炎,直至右眼。在2个月内,病情进展为外侧前庭软骨、上颌内侧壁、鼻甲和鼻中隔软骨坏死。活检报告为非霍奇金弥漫性T细胞(血管中心性T细胞)淋巴瘤。

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本文引用的文献

1
NHL - Extranodal T-cell lymphoma.非霍奇金淋巴瘤 - 结外T细胞淋巴瘤
Natl J Maxillofac Surg. 2015 Jan-Jun;6(1):99-102. doi: 10.4103/0975-5950.168217.
2
Lethal midline granuloma.致死性中线肉芽肿
Indian Dermatol Online J. 2013 Jan;4(1):37-9. doi: 10.4103/2229-5178.105469.
5
Nasal NK/T-cell lymphoma: epidemiology and pathogenesis.鼻型NK/T细胞淋巴瘤:流行病学与发病机制
Int J Hematol. 2008 Mar;87(2):110-117. doi: 10.1007/s12185-008-0021-7. Epub 2008 Feb 8.

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