Imanzadeh Amir, George Elizabeth, Kondo Takeshi, Takase Shinichi, Amanuma Makoto, Rybicki Frank J, Kumamaru Kanako K
Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women's Hospital & Harvard Medical School, Boston, MA, USA.
Department of Cardiology, Takase Clinic, Takasaki, Japan.
Jpn J Radiol. 2016 Feb;34(2):140-7. doi: 10.1007/s11604-015-0506-2. Epub 2015 Dec 15.
To evaluate the role of coronary artery calcium scoring (CACS) and/or coronary CT angiography (CCTA) in asymptomatic elderly patients with high pretest probability for coronary artery disease (CAD).
Forty-eight consecutive asymptomatic elderly (>65 years) subjects who had a high pretest probability and underwent CACS/CCTA were included. Each CCTA was evaluated for adequacy for assessment of coronary stenosis. Significant stenosis (>50% diameter narrowing) was assessed on evaluable CT images and by invasive catheter angiography (ICA).
All subjects were men with mean CACS of 880 ± 1779. Among those with low (0-99), intermediate (100-399), and high (400-999) CACS, ICA-verified significant stenosis was present in 8% (1/13), 23% (2/13), and 67% (8/12), respectively. Among those with very high CACS (≥ 1000) (n = 10), 90% of CCTAs were not evaluable for stenosis.
In asymptomatic elderly subjects with high pretest probability, CACS followed by CCTA may be considered for those with intermediate to high CACS.
评估冠状动脉钙化评分（CACS）和/或冠状动脉CT血管造影（CCTA）在无症状且冠心病（CAD）预测概率高的老年患者中的作用。
纳入48例连续的无症状老年（>65岁）患者，这些患者预测概率高且接受了CACS/CCTA检查。对每例CCTA评估其评估冠状动脉狭窄的充分性。在可评估的CT图像上以及通过有创导管血管造影（ICA）评估显著狭窄（直径狭窄>50%）。
所有受试者均为男性，平均CACS为880±1779。在CACS低（0 - 99）、中（100 - 399）和高（400 - 999）的患者中，经ICA证实的显著狭窄分别为8%（1/13）、23%（2/1
