基于半胱胺修饰金纳米粒子的克伦特罗快速比色传感器。
A Rapid Colorimetric Sensor of Clenbuterol Based on Cysteamine-Modified Gold Nanoparticles.
作者信息
Kang Jingyan, Zhang Yujie, Li Xing, Miao Lijing, Wu Aiguo
机构信息
Faculty of Science, Ningbo University , Ningbo 315211, China.
Key Laboratory of Magnetic Materials and Devices, and Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering , Ningbo 315201, China.
出版信息
ACS Appl Mater Interfaces. 2016 Jan 13;8(1):1-5. doi: 10.1021/acsami.5b09079. Epub 2015 Dec 22.
Demonstrated was a simple visual and rapid colorimetric sensor for detection of clenbuterol (CLB) based on gold nanoparticles (AuNPs) modified with cysteamine (CA) and characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), UV-vis. The solution color from red to blue gray with increasing clenbuterol concentration resulted from the aggregation of AuNPs. The detection limit of clenbuterol is 50 nM by naked eyes. The selectivity of CA-AuNPs detection system for clenbuterol is excellent compared with other interferents in food. This sensor has been successfully applied to detect clenbuterol in real blood sample.
展示了一种基于用半胱胺（CA）修饰的金纳米颗粒（AuNPs）的用于检测克伦特罗（CLB）的简单可视化快速比色传感器，并用透射电子显微镜（TEM）、动态光散射（DLS）、紫外可见光谱对其进行了表征。随着克伦特罗浓度增加，溶液颜色从红色变为蓝灰色，这是由金纳米颗粒的聚集导致的。用肉眼检测克伦特罗的极限为50 nM。与食品中的其他干扰物相比，CA-AuNPs检测系统对克伦特罗的选择性极佳。该传感器已成功应用于实际血液样本中克伦特罗的检测。
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