Ostovar Afshin, Nabipour Iraj, Larijani Bagher, Heshmat Ramin, Darabi Hossein, Vahdat Katayoun, Ravanipour Maryam, Mehrdad Neda, Raeisi Alireza, Heidari Gholamreza, Shafiee Gita, Haeri Mohammadjavad, Pourbehi Mohammadreza, Sharifi Farshad, Noroozi Azita, Tahmasebi Rahim, Aghaei Meybodi Hamidreza, Assadi Majid, Farrokhi Shokrollah, Nemati Reza, Amini Mohammad Reza, Barekat Maryam, Amini Abdullatif, Salimipour Houman, Dobaradaran Sina, Moshtaghi Darab
The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
BMJ Open. 2015 Dec 16;5(12):e009597. doi: 10.1136/bmjopen-2015-009597.
The main objective of the Bushehr Elderly Health Programme, in its first phase, is to investigate the prevalence of cardiovascular risk factors and their association with major adverse cardiovascular events.
Between March 2013 and October 2014, a total of 3000 men and women aged ≥ 60 years, residing in Bushehr, Iran, participated in this prospective cohort study (participation rate=90.2%).
Baseline data on risk factors, including demographic and socioeconomic status, smoking and medical history, were collected through a modified WHO MONICA questionnaire. Vital signs and anthropometric measures, including systolic and diastolic blood pressure, weight, height, and waist and hip circumference, were also measured. 12-lead electrocardiography and echocardiography were conducted on all participants, and total of 10 cc venous blood was taken, and sera was separated and stored at -80 °C for possible future use. Preliminary data analyses showed a noticeably higher prevalence of risk factors among older women compared to that in men.
Risk factor assessments will be repeated every 5 years, and the participants will be followed during the study to measure the occurrence of major adverse cardiac events. Moreover, the second phase, which includes investigation of bone health and cognition in the elderly, was started in September 2015. Data are available at the Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran, for any collaboration.
布什尔老年健康项目第一阶段的主要目标是调查心血管危险因素的患病率及其与主要不良心血管事件的关联。
2013年3月至2014年10月期间,共有3000名年龄≥60岁、居住在伊朗布什尔的男性和女性参与了这项前瞻性队列研究(参与率=90.2%)。
通过修改后的世界卫生组织莫尼卡问卷收集了包括人口统计学和社会经济状况、吸烟和病史等危险因素的基线数据。还测量了生命体征和人体测量指标,包括收缩压和舒张压、体重、身高以及腰围和臀围。对所有参与者进行了12导联心电图和超声心动图检查,并采集了10毫升静脉血,分离出血清并储存在-80°C以备将来可能使用。初步数据分析显示,老年女性中危险因素的患病率明显高于男性。
将每5年重复进行一次危险因素评估,并在研究期间对参与者进行随访,以测量主要不良心脏事件的发生情况。此外,包括对老年人骨骼健康和认知情况进行调查的第二阶段于2015年9月启动。伊朗布什尔医科大学波斯湾生物医学研究所可提供数据,供任何合作使用。