社区老年人中抑郁与血压的相关性研究：以布什尔老年健康（BEH）项目为例。
Association between depression and blood pressure in community-dwelling older adults: focus on Bushehr elderly health (BEH) program.
机构信息
The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran.
出版信息
BMC Public Health. 2023 Aug 17;23(1):1565. doi: 10.1186/s12889-023-16288-1.
INTRODUCTION
Depression and increased blood pressure are significant burdens in elderly care. This study was conducted to discover the association between hypertension (HTN) and depression based on data obtained from the Bushehr Elderly Health (BEH) program in a large population of Iranian elderly in Bushehr, southern Iran.
METHODS
This study was carried out based on data obtained from the Bushehr Elderly Health (BEH) program in a large population of Iranian elderly in Bushehr, a southern city in Iran. 2419 old adults were included in the study through multi-stage random sampling. Depression was assessed using Patient Health Questionnaire-9 (PHQ-9), and blood pressure was measured using a standard mercury sphygmomanometer. Statistical analysis was conducted via chai-square, analysis of variance (ANOVA), and univariate and multivariate linear regression tests.
RESULTS
The mean age of participants was 69.95 ± 6.95 years. The prevalence of depression was 23.8%. Diastolic blood pressure (DBP) decreased with increasing PHQ score (B=-0.001; 95%CI: -0.00 to -0.00, P-value = 0.011). In the final model adjusted for confounding variables, no significant association was found between depression score and DBP (B=-0.00; 95%CI: -0.00 to 0.00, P = 0.13). Conversely, in the final model, which included the confounding variable, SBP was significantly associated with depression. It was deduced that a variable acted as a negative confounder in this association; in a way that with increased depression score, SBP significantly decreased (B=-0.00; 95% CI: -0.00 to -0.00, P = 0.04).
CONCLUSION
Depression and its related medications could be significantly associated with controlled SBP. Health practitioners in primary health care centers must monitor the elderly inflicted with HTN for early symptoms of depression to help maintain blood pressure levels using medicinal and non-medicinal interventions.
简介
在老年护理中，抑郁和血压升高是两个重大负担。本研究旨在通过伊朗南部布什尔省布什尔老年健康（BEH）计划获取的数据，发现伊朗老年人群中高血压（HTN）与抑郁之间的关联。
方法
本研究基于伊朗南部布什尔省布什尔老年健康（BEH）计划获取的大量伊朗老年人数据进行。通过多阶段随机抽样，研究纳入了 2419 名老年人。使用患者健康问卷-9（PHQ-9）评估抑郁，使用标准汞柱血压计测量血压。通过卡方检验、方差分析（ANOVA）以及单变量和多变量线性回归检验进行统计分析。
结果
参与者的平均年龄为 69.95±6.95 岁。抑郁的患病率为 23.8%。随着 PHQ 评分的增加，舒张压（DBP）逐渐降低（B=-0.001；95%CI：-0.00 至-0.00，P 值=0.011）。在调整混杂变量的最终模型中，抑郁评分与 DBP 之间无显著关联（B=-0.00；95%CI：-0.00 至 0.00，P=0.13）。相反，在包含混杂变量的最终模型中，SBP 与抑郁显著相关。可以推断，一个变量在这种关联中充当了负混杂因素；随着抑郁评分的增加，SBP 显著降低（B=-0.00；95%CI：-0.00 至-0.00，P=0.04）。
结论
抑郁及其相关药物可能与控制 SBP 显著相关。初级保健中心的医疗保健工作者必须监测患有 HTN 的老年人，以发现早期抑郁症状，并用药物和非药物干预来帮助维持血压水平。
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