Cancer Res Treat. 2003 Oct;35(5):411-8. doi: 10.4143/crt.2003.35.5.411.
The aim of this study was to examine the associations between depression, anxiety, hostility and fighting spirit among patients with stomach, colorectal or breast cancer.
223 patients, diagnosed as with stomach, colorectal or breast cancer, undergoing chemotherapy or follow up care, were the subjects of the study. The study design was cross-sectional at the time of the survey. The degrees of depression, anxiety and hostility of the patients were assessed by the SCL-90-R scores, and the fighting spirit was measured by the Mental Adjustment to Cancer (MAC) scale score.
The scores of anxiety and hostility of the patients at younger age were higher than those at older age (p<0.01). The patients with metastasis were more depressed than those without it (p<0.01). There was a negative association between depression and fighting spirit (p<0.001).
The study showed the more depressed cancer patients had lower fighting spirit score, which was known to be one of the most active psychosocial contributors in adjusting to cancer and survival.
本研究旨在探讨胃癌、结直肠癌和乳腺癌患者的抑郁、焦虑、敌意与求生意志之间的关系。
本研究共纳入 223 名接受化疗或随访的胃癌、结直肠癌和乳腺癌患者。采用 SCL-90-R 评估患者的抑郁、焦虑和敌意程度，采用癌症心理调整问卷（MAC）评估患者的求生意志。
年龄较小的患者焦虑和敌意得分高于年龄较大的患者（p<0.01）。发生转移的患者比未发生转移的患者抑郁得分更高（p<0.01）。抑郁与求生意志呈负相关（p<0.001）。
本研究表明，抑郁程度越严重的癌症患者，其求生意志得分越低，而求生意志是癌症适应和生存的最积极的心理社会因素之一。
