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Synthetic lethality in KRas-driven cancer cells created by glutamine deprivation.

作者信息

Mukhopadhyay Suman, Saqcena Mahesh, Foster David A

机构信息

Department of Biological Sciences, Hunter College of the City University of New York, New York, NY, USA; Department of Pharmacology, Weill-Cornell Medical College, New York, NY, USA.

出版信息

Oncoscience. 2015 Sep 23;2(10):807-8. doi: 10.18632/oncoscience.253. eCollection 2015.

DOI:10.18632/oncoscience.253
PMID:26682255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4671930/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e991/4671930/aa177e01927d/oncoscience-02-0807-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e991/4671930/aa177e01927d/oncoscience-02-0807-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e991/4671930/aa177e01927d/oncoscience-02-0807-g001.jpg

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Cell. 2015 Jul 30;162(3):540-51. doi: 10.1016/j.cell.2015.07.016.
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Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle.
WEE1抑制剂阿伐斯替尼对结直肠癌具有抗肿瘤作用，尤其是在存在突变的病例中。
Cancers (Basel). 2024 Sep 12;16(18):3136. doi: 10.3390/cancers16183136.
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Exploring the Role of CBX3 as a Potential Therapeutic Target in Lung Cancer.探索CBX3作为肺癌潜在治疗靶点的作用。
Cancers (Basel). 2024 Aug 30;16(17):3026. doi: 10.3390/cancers16173026.
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Application of PARP inhibitors combined with immune checkpoint inhibitors in ovarian cancer.PARP 抑制剂联合免疫检查点抑制剂在卵巢癌中的应用。
J Transl Med. 2024 Aug 21;22(1):778. doi: 10.1186/s12967-024-05583-z.
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