INSERM, UMR912 "Economics and Social Sciences Applied to Health & Analysis of Medical Information" (SESSTIM), 13385, Marseille, France.
Aix Marseille Université, UMR_S912, IRD, 13385, Marseille, France.
J Cancer Surviv. 2016 Jun;10(3):600-9. doi: 10.1007/s11764-015-0506-3. Epub 2015 Dec 21.
The purpose of this study is to assess French cancer survivors' sexual health 2 years after diagnosis.
Using the French National Health Insurance System database, the representative national VICAN survey was created comprising 4349 adults (12 cancer sites), still alive 2 years after diagnosis and aged 18-52 ("younger") or 53-82 ("older"). Sexual health was evaluated using six items from the Relationship and Sexuality Scale, and an overall indicator was created.
Among the study's 1955 sexually active participants, 18.6 % (versus 13.1 %), 39.8 % (versus 39.9 %) and 29.4 % (versus 29.8 %) of men (versus women) were affected, respectively, by "strong", "moderate" and "weak" sexual health deterioration, while 12.2 % (versus 17.1 %) were spared sexual problems (P = 0.001). Strong deterioration more often concerned older men with prostate (27.7 %) and lung (26.1 %) cancers, younger men with upper aero-digestive tract cancers (25.2 %) and women (younger/older) with cervical cancer (24.2 %). Substantial (strong/moderate) sexual health deterioration was observed for all cancer sites, rates ranging from 68.3 % (prostate) to 37.2 % (melanoma). In all four gender/age subgroups, increasing age predicted poorer sexual health, although statistical significance was not reached in older women. Apart from genital cancer, perceived consequences, such as general sequelae and fatigue, were the primary factors associated with severe sexual problems.
Two years after diagnosis, the majority of sexually active French cancer survivors reported impaired sexual health. Younger and older men and women with cancer in non-reproductive sites also reported problems.
Interventions aimed at improving sexual health irrespective of age and cancer site should be developed.
本研究旨在评估诊断后 2 年内法国癌症幸存者的性健康状况。
利用法国国家健康保险系统数据库，创建了具有代表性的全国性 VICAN 调查，该调查包含 4349 名成年人（12 个癌症部位），在诊断后 2 年内仍存活，年龄在 18-52 岁（“年轻”组）或 53-82 岁（“年老”组）。使用关系和性行为量表的六个项目评估性健康，并创建了一个整体指标。
在 1955 名有性行为的研究参与者中，分别有 18.6%（13.1%）、39.8%（39.9%）和 29.4%（29.8%）的男性（女性）出现“强”、“中”和“弱”性健康恶化，而 12.2%（17.1%）没有性问题（P=0.001）。性健康恶化更常见于前列腺（27.7%）和肺癌（26.1%）的老年男性、上呼吸道和消化道癌症（25.2%）的年轻男性以及宫颈癌（24.2%）的女性（年轻/年老）。所有癌症部位都观察到明显（强/中）的性健康恶化，发生率从前列腺癌的 68.3%到黑色素瘤的 37.2%不等。在所有四个性别/年龄亚组中，年龄的增加预示着性健康状况较差，尽管在老年女性中未达到统计学意义。除生殖部位癌症外，一般后遗症和疲劳等感知后果是与严重性问题相关的主要因素。
诊断后 2 年内，大多数有性行为的法国癌症幸存者报告性健康受损。非生殖部位癌症的年轻和老年男性和女性也报告存在问题。
无论年龄和癌症部位如何，都应开发旨在改善性健康的干预措施。
