Yang Chun, Chen Jing, Liu Zhen, Yun Chunfeng, Li Yajie, Piao Jianhua, Yang Xiaoguang
Key Laboratory of Trace Element Nutrition, National Health and Family Planning Commission of China, Department of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Int J Environ Res Public Health. 2015 Dec 7;12(12):15531-9. doi: 10.3390/ijerph121214998.
This study was conducted to examine the possible association between vitamin A status and overnutrition in Chinese urban children and adolescents. Weight, height and serum retinol were assessed in total 3457 children (7-9.9 years of age) and adolescents (10-17 years of age), using urban region data from the China National Nutrition and Health Survey 2010-2013 (CHNNS2010-2013) which is a nationally representative cross-sectional study. Prevalence of low serum concentration of retinol was 26.8% and 12.24% for overweight. Retinol inadequacy was significantly higher in children (32.13%) than in adolescents (24.48%). The average of retinol was significantly higher in overnutrified 42.32 μg/dL versus non-overnutrified 41.05 μg/dL (p = 0.00) children and adolescents. Overnutrified children and adolescents presented a greater chance of an increase in serum concentration of retinol (odds ratio 1.34, 95% confidence interval 1.10-1.63, and 1.48, 95% confidence interval (1.26-1.74) when compared with non-overnutrified children. An important correspondence between vitamin A deficiency and overnutrition was found. Non-overnutrified children and adolescents may have a greater chance of presenting low concentrations of retinol. Future public health strategies focused on the overnutrified population and vitamin A supplements should consider the effect of retinol on urban children and adolescents in China.
本研究旨在探讨中国城市儿童和青少年维生素A状况与营养过剩之间的可能关联。利用2010 - 2013年中国国家营养与健康调查（CHNNS2010 - 2013）的城市地区数据，对总共3457名儿童（7 - 9.9岁）和青少年（10 - 17岁）进行了体重、身高和血清视黄醇评估，该调查是一项具有全国代表性的横断面研究。血清视黄醇浓度低的患病率为26.8%，超重患病率为12.24%。儿童（32.13%）的视黄醇不足率显著高于青少年（24.48%）。营养过剩的儿童和青少年血清视黄醇平均值（42.32μg/dL）显著高于非营养过剩者（41.05μg/dL，p = 0.00）。与非营养过剩儿童相比，营养过剩的儿童和青少年血清视黄醇浓度升高的可能性更大（优势比1.34，95%置信区间1.10 - 1.63；以及1.48，95%置信区间1.26 - 1.74）。发现维生素A缺乏与营养过剩之间存在重要关联。非营养过剩的儿童和青少年可能更有可能出现低视黄醇浓度。未来针对营养过剩人群和维生素A补充剂的公共卫生策略应考虑视黄醇对中国城市儿童和青少年的影响。
