Tuulonen A, Koponen J, Alanko H I, Airaksinen P J
Department of Ophthalmology, University of Oulu, Finland.
Acta Ophthalmol (Copenh). 1989 Jun;67(3):275-80. doi: 10.1111/j.1755-3768.1989.tb01871.x.
The first-year results of a 5-year prospective randomized follow-up study on 39 glaucoma patients, of whom 19 patients received laser trabeculoplasty and 20 patients medication therapy as primary treatment of their newly detected open-angle glaucoma, are presented. The optic disc changes were recorded by measuring the magnification corrected neuroretinal rim area from stereoscopic optic disc photographs and the visual field changes with an automated perimeter. There were no statistically significant differences in success rate, intraocular pressure reduction, and optic disc or visual field changes between the two groups during the first year of follow-up. In half of the laser treated patients the intraocular pressure was below 22 mmHg without medication treatment. Many patients in the medication group required frequent modifications of their therapy. Laser trabeculoplasty has an important role as primary therapy in glaucoma.
本文展示了一项针对39例青光眼患者的5年前瞻性随机随访研究的第一年结果。其中19例患者接受了激光小梁成形术，20例患者接受药物治疗作为新诊断开角型青光眼的初始治疗。通过测量立体视盘照片中放大校正后的神经视网膜边缘面积记录视盘变化，并使用自动视野计记录视野变化。在随访的第一年，两组在成功率、眼压降低以及视盘或视野变化方面均无统计学显著差异。在接受激光治疗的患者中，一半患者在未进行药物治疗的情况下眼压低于22 mmHg。药物治疗组的许多患者需要频繁调整治疗方案。激光小梁成形术在青光眼的初始治疗中具有重要作用。
