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原发性氩激光小梁成形术与毛果芸香碱。III. 对视野的长期影响。

Primary argon laser trabeculoplasty vs pilocarpine. III. Long-term effects on visual fields.

作者信息

Bergeå B, Bodin L, Svedbergh B

机构信息

Department of Ophthalmology, Orebro Medical Center Hospital, Sweden.

出版信息

Acta Ophthalmol Scand. 1995 Jun;73(3):207-15. doi: 10.1111/j.1600-0420.1995.tb00270.x.

DOI:10.1111/j.1600-0420.1995.tb00270.x
PMID:7493230
Abstract

In a prospective randomized study on primary argon laser trabeculoplasty vs pilocarpine in 82 newly detected open-angle glaucoma patients, visual field changes were analysed for absolute changes over 2 years on automated threshold perimetry and manual Goldmann perimetry. Regression analysis was also performed using the threshold perimetry examinations taken every second month. Analyses based on automatic perimetry were corrected for eventual bias due to cataract and induced miosis. There was significantly less decay of visual field in the group treated with laser. This was even more pronounced for eyes with capsular glaucoma, especially in the early stage. For the smaller group with simple glaucoma no significant advantage of laser could be shown. Successful intraocular pressure reduction significantly improved the visual field outcome. Laser trabeculoplasty is therefore recommended as primary therapy in capsular glaucoma.

摘要

在一项针对82例新诊断的开角型青光眼患者进行的原发性氩激光小梁成形术与毛果芸香碱的前瞻性随机研究中,通过自动阈值视野计和手动戈德曼视野计分析了2年期间视野的绝对变化。还使用每两个月进行一次的阈值视野检查进行了回归分析。基于自动视野计的分析针对白内障和诱导性瞳孔缩小导致的最终偏差进行了校正。激光治疗组的视野衰退明显较少。这在晶状体囊膜性青光眼患者中更为明显,尤其是在早期。对于单纯性青光眼的较小患者组,未显示出激光治疗有明显优势。成功降低眼压可显著改善视野结果。因此,推荐激光小梁成形术作为晶状体囊膜性青光眼的主要治疗方法。

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