Bergeå B, Bodin L, Svedbergh B
Department of Ophthalmology, Orebro Medical Center Hospital, Sweden.
Acta Ophthalmol (Copenh). 1994 Apr;72(2):145-54. doi: 10.1111/j.1755-3768.1994.tb05008.x.
In a prospective study 82 patients recently diagnosed with simple or capsular glaucoma were randomized to receive primary argon laser trabeculoplasty or pilocarpine treatment. A 2-year follow-up showed a better success rate in the laser group, with less need for additional therapy. The average intraocular pressure and peak pressure was lower and the daytime pressure variation was significantly less in the laser group. The better increase in facility of outflow in the laser group was not statistically significant. In capsular glaucoma, laser treatment resulted in a significantly lower average pressure than with medication. In simple glaucoma the effect was about the same in the two treatment groups. Increase in facility of outflow was significantly better in simple glaucoma than in capsular glaucoma. High initial intraocular pressure gave a significantly lower success rate. Primary argon laser trabeculoplasty as a single glaucoma treatment seems advantageous in comparison to medication with pilocarpine for regulating intraocular pressure.
在一项前瞻性研究中，82例近期诊断为原发性或囊膜性青光眼的患者被随机分为接受原发性氩激光小梁成形术或毛果芸香碱治疗两组。2年的随访显示，激光治疗组的成功率更高，且较少需要额外治疗。激光治疗组的平均眼压和峰值眼压更低，日间眼压波动也明显更小。激光治疗组房水流畅系数的改善虽未达到统计学显著差异。在囊膜性青光眼中，激光治疗的平均眼压显著低于药物治疗。在原发性青光眼中，两种治疗组的效果大致相同。原发性青光眼中房水流畅系数的改善显著优于囊膜性青光眼。初始眼压较高时成功率显著较低。与毛果芸香碱药物治疗相比，原发性氩激光小梁成形术作为单一的青光眼治疗方法在调节眼压方面似乎更具优势。
