González García Andrés, Fernández Emiliano Grillo, Barbolla Díaz Ignacio, Ballester Asunción, Pian Héctor, Fraile Guadalupe
Department of Internal Medicine, University Hospital Ramón y Cajal, Madrid, Spain.
Department of Dermatology, University Hospital Ramón y Cajal, Madrid, Spain.
Case Rep Dermatol Med. 2015;2015:415393. doi: 10.1155/2015/415393. Epub 2015 Nov 30.
From a clinical point of view, the most common presentations of cutaneous metastatic disease are papules and nodules. However, a wide morphological spectrum of lesions has been described, including erythematous patches or plaques, inflammatory erysipelas-like lesions, diffuse sclerodermiform lesions with induration of the skin, telangiectatic papulovesicles, purpuric plaques mimicking vasculitis, and alopecia areata like scalp lesions. The so-called zosteriform pattern has been described to be in few cases and to the best of our knowledge has never been described associated with a metastasis of a nasopharyngeal carcinoma. This case highlights the relevance of including cutaneous metastases in the differential diagnosis of patients with nonhealing herpes zoster-like lesions, especially in those with underlying neoplasm recently diagnosed.
从临床角度来看,皮肤转移性疾病最常见的表现是丘疹和结节。然而,已描述的病变形态谱很广,包括红斑性斑片或斑块、炎性丹毒样病变、皮肤硬化样弥漫性病变伴皮肤硬结、毛细血管扩张性丘疹水疱、类似血管炎的紫癜性斑块以及斑秃样头皮病变。所谓的带状疱疹样模式在少数病例中已有描述,据我们所知,从未有过与鼻咽癌转移相关的描述。该病例凸显了在鉴别诊断不愈合的带状疱疹样病变患者时,尤其是那些近期诊断出有潜在肿瘤的患者,纳入皮肤转移瘤的重要性。