Hasegawa Kohei, Camargo Carlos A
Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Respirology. 2016 May;21(4):761-4. doi: 10.1111/resp.12724. Epub 2015 Dec 23.
In this cohort of 3084 patients hospitalized for acute exacerbation of COPD (AECOPD), we found that 17% had blood eosinophilia (≥300 cells/μL); the use of an alternative cut-off level (≥2%) demonstrated that 40% had elevated eosinophil count. Patients with eosinophilia had higher frequency of readmission for AECOPD during 1-year follow-up period. This is the first study to investigate the prevalence of eosinophilia among inpatients with AECOPD--the population with the highest morbidity and health-care utilization.
在这组3084例因慢性阻塞性肺疾病急性加重（AECOPD）住院的患者中，我们发现17%的患者存在血嗜酸性粒细胞增多（≥300个细胞/μL）；采用另一个临界值水平（≥2%）显示，40%的患者嗜酸性粒细胞计数升高。嗜酸性粒细胞增多的患者在1年随访期内因AECOPD再次入院的频率更高。这是第一项调查AECOPD住院患者（发病率和医疗保健利用率最高的人群）中嗜酸性粒细胞增多患病率的研究。
