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过去50年里小儿软组织肉瘤分类的演变

The Evolution of Pediatric Soft Tissue Sarcoma Classification in the Last 50 Years.

作者信息

Alaggio Rita, Coffin Cheryl M

机构信息

1 Department of Medicine-DIMED, Pathology Unit, University of Padova, Via Gabelli, 61 35124, Padova, Italy.

2 Department of Pathology, Vanderbilt Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.

出版信息

Pediatr Dev Pathol. 2015 Nov-Dec;18(6):481-94. doi: 10.2350/15-07-1666-MISC.1. Epub 2015 Dec 23.

DOI:10.2350/15-07-1666-MISC.1
PMID:26701753
Abstract

This review discusses the history of the classification of soft tissue sarcomas in children and adolescents, the current transition toward integration of morphology and molecular genetics as new entities emerge, and future perspectives.

摘要

本综述讨论了儿童和青少年软组织肉瘤的分类历史、随着新实体出现当前向形态学和分子遗传学整合的转变以及未来展望。

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The Evolution of Pediatric Soft Tissue Sarcoma Classification in the Last 50 Years.过去50年里小儿软组织肉瘤分类的演变
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Durable Clinical Response to Larotrectinib in an Adolescent Patient With an Undifferentiated Sarcoma Harboring an - Fusion.一名患有未分化肉瘤且携带 - 融合的青少年患者对拉罗替尼产生持久临床反应。
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DNA Methylation Profiling for Diagnosing Undifferentiated Sarcoma with Capicua Transcriptional Receptor () Alterations.
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The Brazilian TP53 mutation (R337H) and sarcomas.巴西 TP53 突变(R337H)与肉瘤。
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Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins.横纹肌肉瘤和肾母细胞瘤含有一群产生诺金的、肌源性细胞,这些细胞对晶状体珠状丝蛋白呈免疫反应性。
PLoS One. 2019 Apr 11;14(4):e0214758. doi: 10.1371/journal.pone.0214758. eCollection 2019.
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Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.小儿肉瘤和脑肿瘤中的精氨酸营养缺陷型基因特征为精氨酸剥夺疗法提供了一个可行的靶点。
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