Phan Long, Kautz Rylan, Arulmoli Janahan, Kim Iris H, Le Dai Trang T, Shenk Michael A, Pathak Medha M, Flanagan Lisa A, Tombola Francesco, Gorodetsky Alon A
Department of Chemical Engineering and Materials Science, University of California, Irvine , Irvine, California 92697, United States.
Department of Biomedical Engineering, University of California, Irvine , Irvine, California 92697, United States.
ACS Appl Mater Interfaces. 2016 Jan 13;8(1):278-84. doi: 10.1021/acsami.5b08717. Epub 2015 Dec 24.
Cephalopods possess remarkable camouflage capabilities, which are enabled by their complex skin structure and sophisticated nervous system. Such unique characteristics have in turn inspired the design of novel functional materials and devices. Within this context, recent studies have focused on investigating the self-assembly, optical, and electrical properties of reflectin, a protein that plays a key role in cephalopod structural coloration. Herein, we report the discovery that reflectin constitutes an effective material for the growth of human neural stem/progenitor cells. Our findings may hold relevance both for understanding cephalopod embryogenesis and for developing improved protein-based bioelectronic devices.
头足类动物具有非凡的伪装能力,这得益于它们复杂的皮肤结构和精密的神经系统。这些独特的特性反过来又激发了新型功能材料和设备的设计灵感。在此背景下,最近的研究集中于探究反射蛋白的自组装、光学和电学特性,反射蛋白在头足类动物的结构色形成中起着关键作用。在此,我们报告一项发现,即反射蛋白是人类神经干细胞/祖细胞生长的有效材料。我们的发现可能对理解头足类动物胚胎发育以及开发改良的基于蛋白质的生物电子设备都具有重要意义。