Tian Bozhi, Xu Shuai, Rogers John A, Cestellos-Blanco Stefano, Yang Peidong, Carvalho-de-Souza João L, Bezanilla Francisco, Liu Jia, Bao Zhenan, Hjort Martin, Cao Yuhong, Melosh Nicholas, Lanzani Guglielmo, Benfenati Fabio, Galli Giulia, Gygi Francois, Kautz Rylan, Gorodetsky Alon A, Kim Samuel S, Lu Timothy K, Anikeeva Polina, Cifra Michal, Krivosudský Ondrej, Havelka Daniel, Jiang Yuanwen
Department of Chemistry, University of Chicago, Chicago, IL 60637, United States of America.
Phys Biol. 2018 Mar 9;15(3):031002. doi: 10.1088/1478-3975/aa9f34.
This roadmap outlines the role semiconductor-based materials play in understanding the complex biophysical dynamics at multiple length scales, as well as the design and implementation of next-generation electronic, optoelectronic, and mechanical devices for biointerfaces. The roadmap emphasizes the advantages of semiconductor building blocks in interfacing, monitoring, and manipulating the activity of biological components, and discusses the possibility of using active semiconductor-cell interfaces for discovering new signaling processes in the biological world.
本路线图概述了基于半导体的材料在理解多长度尺度下复杂生物物理动力学方面所发挥的作用,以及用于生物界面的下一代电子、光电子和机械设备的设计与实现。该路线图强调了半导体组件在连接、监测和操纵生物组件活性方面的优势,并讨论了利用活性半导体-细胞界面发现生物界新信号传导过程的可能性。