尼日利亚拉各斯儿童结核病的治疗结果
Treatment Outcomes of Childhood TB in Lagos, Nigeria.
作者信息
Adejumo Olusola Adedeji, Daniel Olusoji James, Adebayo Bisola Ibironke, Adejumo Esther Ngozi, Jaiyesimi Ebunoluwa Olasumbo, Akang Gabriel, Awe Ayodele
机构信息
Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital Lagos, Nigeria
Department of Community Medicine and Primary Care Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria.
出版信息
J Trop Pediatr. 2016 Apr;62(2):131-8. doi: 10.1093/tropej/fmv089. Epub 2015 Dec 24.
BACKGROUND
: Treatment outcomes of tuberculosis (TB) in children are rarely evaluated by most national TB programmes in sub-Saharan Africa. This study evaluated the treatment outcomes of children treated for TB in Lagos State, Nigeria.
METHODS
A retrospective review of programme data of the Lagos state TB and the Leprosy control programme in Nigeria from 1 January 2012 to 31 December 2012. Treatment outcomes were categorized according to the national TB guidelines.
RESULTS
A total of 535 cases of childhood TB were notified in 2012, representing 6.3% of the total TB cases notified in Lagos state in 2012. The prevalence of TB/HIV co-infection was 29%. The treatment success rate was 79.2% in TB/HIV-negative children compared with 73.4% in TB/HIV-positive children (p = 0.1268). Children <1 year had the worst treatment outcomes (p < 0.001).
CONCLUSION
There is a need to intensify effort at improving notification and treatment outcomes in children.
背景
撒哈拉以南非洲的大多数国家结核病规划很少评估儿童结核病的治疗结果。本研究评估了尼日利亚拉各斯州接受结核病治疗的儿童的治疗结果。
方法
对尼日利亚拉各斯州结核病和麻风病控制规划2012年1月1日至2012年12月31日的规划数据进行回顾性审查。治疗结果根据国家结核病指南进行分类。
结果
2012年共报告535例儿童结核病病例，占2012年拉各斯州报告的结核病病例总数的6.3%。结核病/艾滋病毒合并感染率为29%。结核病/艾滋病毒阴性儿童的治疗成功率为79.2%，而结核病/艾滋病毒阳性儿童为73.4%（p = 0.1268）。1岁以下儿童的治疗结果最差（p < 0.001）。
结论
有必要加大力度改善儿童结核病的报告和治疗结果。
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