Souza Felix Bravo Bruna, Klotz De Almeida Balassiano Laila, Roos Mariano Da Rocha Camila, Barbosa De Sousa Padilha Carolina, Martinezt Torrado Carolina, Teixeira Da Silva Roberta, Carlos Regazzi Avelleira João
Institute de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro and Hospital Federal da Lagoa - Rio de Janeiro, Brazil;
Policlinica Geral do Rio de Janeiro, Brazil;
J Clin Aesthet Dermatol. 2015 Dec;8(12):42-7.
The growing use of dermal fillers, specifically the use of hyaluronic acid, can be explained by their effectiveness and versatility as well as their favorable safety profiles. Nevertheless, early and late complications with varying levels of severity may occur. The incidence of complications is low and the majority of adverse events are mild (edema, erythema, and local ecchymosis) and of limited duration. However, more severe events, such as ischemia and necrosis, may occur. The symptoms of ischemia can occur immediately after the injection or several hours after the procedure. Here, the authors report three cases of necrosis after hyaluronic acid injection with the first symptoms presenting only several hours after the procedure. The patients were treated immediately after the diagnosis. The aim of this review is to communicate the possibility of the delayed-type presentation of necrosis, present the signs and symptoms that lead to early diagnosis, and review the treatment possibilities of this severe complication.
皮肤填充剂的使用日益增加，尤其是透明质酸的使用，这可以通过其有效性、多功能性以及良好的安全性来解释。然而，可能会出现严重程度不同的早期和晚期并发症。并发症的发生率较低，大多数不良事件较轻（水肿、红斑和局部瘀斑）且持续时间有限。然而，可能会发生更严重的事件，如缺血和坏死。缺血症状可在注射后立即出现或术后数小时出现。在此，作者报告了3例透明质酸注射后坏死的病例，最初症状仅在术后数小时出现。诊断后患者立即接受治疗。本综述的目的是告知坏死延迟出现的可能性，呈现导致早期诊断的体征和症状，并回顾这种严重并发症的治疗可能性。
