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大西洋EFS中心供体生物样本库:十年样本使用情况

EFS Centre-Atlantique donor's biobank: Ten years of samples usage.

作者信息

Sapey T, Py J-Y, Barnoux M, Tessier M, Dehaut F

机构信息

EFS Centre-Atlantique Châteauroux/Bourges, Châteauroux/Bourges, France.

EFS Centre-Atlantique Orléans, Orléans, France.

出版信息

Transfus Clin Biol. 2016 May;23(2):95-7. doi: 10.1016/j.tracli.2015.11.002. Epub 2015 Dec 17.

DOI:10.1016/j.tracli.2015.11.002
PMID:26711889
Abstract

INTRODUCTION

The French Establishment of Blood Centre Atlantique (EFSCA) is one of the French regional blood transfusion centers. Donor's biobank is a mandatory activity leading to the storage of biological samples taken from the blood donor. Samples of each blood donation are preserved for a 5-year period at Châteauroux in the form of two straws of 500microliters stored in liquid nitrogen. The aim of this study was to analyze the samples usage by studying quantitative, qualitative and economic criteria.

MATERIAL AND METHOD

We analyzed all the requests of stored blood samples from 2005 to 2014. They were coming either from the blood donor qualification laboratory (BDQL), in order to perform complementary tests, or from hemovigilance inquiry.

RESULTS

Among the blood donation samples, 2,144,636 (whole blood, plasma or platelets apheresis) were preserved during these ten years. During this period, 548 (0.025%) requests for samples were received; 78% were in relation with a request of the BDQL and 22% in relation with a request of hemovigilance. For the straws, the mean exit delay with regard to the blood donation date was 11.5 months (2-55). The cost of samples exit includes only working hours of a laboratory technician. On average, the annual working time dedicated to this activity was 23h. Also, the average price for one-year issuing activity was 620.31 euros.

CONCLUSION

In our study, the donor's biobank was little used. The part of hemovigilance was weak but essential for the blood safety.

摘要

引言

法国大西洋血液中心(EFSCA)是法国的地区输血中心之一。献血者生物样本库是一项强制性活动,用于存储从献血者采集的生物样本。每次献血的样本以两根500微升的吸管形式保存在沙托鲁,液氮储存5年。本研究的目的是通过研究定量、定性和经济标准来分析样本的使用情况。

材料与方法

我们分析了2005年至2014年期间所有储存血液样本的请求。这些请求要么来自献血者资格鉴定实验室(BDQL),以便进行补充检测,要么来自血液警戒调查。

结果

在这十年间,共保存了2,144,636份献血样本(全血、血浆或单采血小板)。在此期间,共收到548份(0.025%)样本请求;其中78%与BDQL的请求有关,22%与血液警戒调查的请求有关。对于吸管,相对于献血日期的平均取出延迟为11.5个月(2 - 55个月)。样本取出的成本仅包括一名实验室技术员的工作时间。平均而言,每年用于这项活动的工作时间为23小时。此外,一年发放活动的平均价格为620.31欧元。

结论

在我们的研究中,献血者生物样本库的使用较少。血液警戒部分虽薄弱,但对血液安全至关重要。

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