Hamajima N, Sasaki R, Shibata A, Suzuki S, Tamakoshi A, Aoki K
Nihon Gan Chiryo Gakkai Shi. 1989 Mar 20;24(3):579-84.
Proportional hazard model was proposed by Cox as a multivariate model suitable for evaluation of prognostic factors and/or therapeutic effects. This paper aims at explaining fundamental concepts of the model for clinical researchers, as clear as possible. The relationship between hazard ratio and survival curves is demonstrated using an example of survivals calculated from an exponential function. Usage of computer programme SAS is described in brief for the readers who plan to analyse their own clinical data by this model.
比例风险模型由考克斯提出,是一种适用于评估预后因素和/或治疗效果的多变量模型。本文旨在尽可能清晰地向临床研究人员解释该模型的基本概念。通过一个由指数函数计算得出的生存示例,展示了风险比与生存曲线之间的关系。对于计划使用该模型分析自身临床数据的读者,简要介绍了计算机程序SAS的用法。