Messeha Medhat M, Elhesy Abd-Elmonem
Department of Anesthesia and Surgical Intensive Care, Mansoura University Hospital, Mansoura, Egypt.
Department of Ophthalmology, Faculty of Medicine, Mansoura Ophthalmology Center, Mansoura University, Mansoura, Egypt.
Anesth Essays Res. 2015 Sep-Dec;9(3):374-8. doi: 10.4103/0259-1162.164649.
The aim of this study was to compare orbital muscle akinesia caused by rocuronium versus hyaluronidase when mixed with the local anesthetic in single-injection peribulbar anesthesia (PBA).
Sixty patients were included in the study and subjected to cataract extraction using phacoemulsification technique with intraocular lens implantation. Group I received peribulbar block with 5 ml mixture of 30 IU/ml hyaluronidase and 2% lidocaine. Group II received peribulbar block with 5 ml mixture of rocuronium 5 mg and 2% lidocaine. The onset and duration of akinesia were assessed; the akinesia score at 2, 5, and 10 min was measured after injection. The need for supplementary injection was also recorded.
PBA using a mixture of rocuronium and lidocaine provides optimal globe akinesia and faster establishment of suitable conditions to start eye surgery and shortens the block onset time as compared with the addition of hyaluronidase to lidocaine.
本研究的目的是比较罗库溴铵与透明质酸酶在与局部麻醉剂混合用于单次球周麻醉（PBA）时引起的眼眶肌肉运动不能情况。
60例患者纳入本研究，并采用超声乳化白内障吸除联合人工晶状体植入术。第一组接受球周阻滞，使用30 IU/ml透明质酸酶与2%利多卡因的5 ml混合液。第二组接受球周阻滞，使用5 mg罗库溴铵与2%利多卡因的5 ml混合液。评估运动不能的起效时间和持续时间；注射后测量2分钟、5分钟和10分钟时的运动不能评分。还记录了追加注射的需求。
与在利多卡因中添加透明质酸酶相比，使用罗库溴铵和利多卡因的混合液进行球周麻醉可提供最佳的眼球运动不能效果，能更快建立适合开始眼科手术的条件，并缩短阻滞起效时间。
