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复发性抑郁症中的认知与情绪——炎症和犬尿氨酸途径的作用

Cognition and Emotions in Recurrent Depressive Disorders - The Role of Inflammation and the Kynurenine Pathway.

作者信息

Talarowska Monika, Galecki Piotr

机构信息

Department of Adult Psychiatry, Medical University of Lodz, Lodz, Poland, Aleksandrowska 159, 91- 229, Lodz;.

出版信息

Curr Pharm Des. 2016;22(8):955-62. doi: 10.2174/1381612822666151230110738.

DOI:10.2174/1381612822666151230110738
PMID:26714730
Abstract

Separating emotions from cognition seems impossible in everyday experiences of a human being. Emotional processes have an impact on the ability of planning and solving problems, or decision-making skills. They are a valuable source of information about ourselves, our partners in interactions and the surrounding world. Recent years have shown that axial symptoms of depression are caused by emotion regulation disorders, dysfunctions in the reward system and deficits of cognitive processes. There is a few studies concerning a link between emotional and inflammatory processes in depression. The aim of this article is to present results of contemporary research studies over mutual connections between social cognition, cognitive processes and inflammatory factors significant for the aetiology of recurrent depressive disorders, with particular reference to the role of kynurenine pathways.

摘要

在人类的日常经历中,将情感与认知分离似乎是不可能的。情感过程会影响规划和解决问题的能力或决策技能。它们是有关我们自身、互动中的伙伴以及周围世界的宝贵信息来源。近年来已表明,抑郁症的轴性症状是由情绪调节障碍、奖赏系统功能障碍和认知过程缺陷引起的。关于抑郁症中情感与炎症过程之间的联系,相关研究较少。本文的目的是介绍当代研究的结果,这些研究涉及社会认知、认知过程和对复发性抑郁症病因学具有重要意义的炎症因子之间的相互关系,尤其提及犬尿氨酸途径的作用。

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Cognition and Emotions in Recurrent Depressive Disorders - The Role of Inflammation and the Kynurenine Pathway.复发性抑郁症中的认知与情绪——炎症和犬尿氨酸途径的作用
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