Rambold Holger A
Department of Neurology, County Hospitals of Altötting and Burghausen, Altötting Department of Neurology, University of Regensburg, Regensburg, Germany.
Otol Neurotol. 2016 Feb;37(2):171-8. doi: 10.1097/MAO.0000000000000947.
To examine "refixating saccades" in the three-dimensional video-head impulse test (vHIT) depending on the age and compare them to refixating saccades in pathological vHIT.
Retrospective database study.
County hospital, specialized vertigo center.
Eight hundred ninety-nine patients without a peripheral vestibular hypofunction were tested with the three-dimensional vHIT and compared with 135 patients with unilateral vestibular hypofunction (UVF).
Occurrence and peak velocity of refixating saccades (covert and overt) during the video-head-impulse test (vHIT) in three age groups (0-30, 30-60, and 60-100 yr) and in UVF.
Overt saccade frequency of refixating saccades increased with increasing age, especially in the horizontal and posterior vHIT. Saccades were mostly directed opposite to the head movement. The aging effect was not explained by the VOR-gain decrease. Refixating saccades in normal vHIT were less frequent and slower than in UVF.
We conclude that refixating saccades increase with higher age and could be differentiated from those in UVF by frequency and peak velocity. Saccades are not caused by a deficient VOR but might be caused by a deficient suppression of saccades to novel targets.
根据年龄研究三维视频头脉冲试验（vHIT）中的“重新注视扫视”，并将其与病理性vHIT中的重新注视扫视进行比较。
回顾性数据库研究。
县医院，专业眩晕中心。
899例无外周前庭功能减退的患者接受了三维vHIT检测，并与135例单侧前庭功能减退（UVF）患者进行了比较。
三个年龄组（0 - 30岁、30 - 60岁和60 - 100岁）以及UVF患者在视频头脉冲试验（vHIT）期间重新注视扫视（隐蔽和明显）的发生率和峰值速度。
重新注视扫视的明显扫视频率随年龄增长而增加，尤其是在水平和后向vHIT中。扫视大多与头部运动方向相反。老化效应不能用前庭眼反射（VOR）增益降低来解释。正常vHIT中的重新注视扫视比UVF中的频率更低且速度更慢。
我们得出结论，重新注视扫视随年龄增长而增加，并且可以通过频率和峰值速度与UVF中的扫视相区分。扫视不是由VOR缺陷引起的，而是可能由对新目标的扫视抑制不足引起的。
