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经主动脉导管排气在静脉-动脉体外膜肺氧合治疗心源性休克患者中的初步经验

Initial Experience of Transaortic Catheter Venting in Patients with Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock.

作者信息

Hong Tae Hee, Byun Joung Hun, Lee Hee Moon, Kim Yong Hwan, Kang Gu-Hyun, Oh Ju Hyeon, Hwang Sang Won, Kim Han Yong, Park Jae Hong, Jung Jae Jun

机构信息

From the *Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; †Department of Emergency Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South Korea; ‡Department of Cardiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South Korea; §Department of Thoracic and Cardiovascular Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South Korea and ¶Present address: Department of Thoracic and Cardiovascular Surgery, Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, South Korea.

出版信息

ASAIO J. 2016 Mar-Apr;62(2):117-22. doi: 10.1097/MAT.0000000000000327.

Abstract

Extracorporeal membrane oxygenation (ECMO) has become one of the often applied mechanical support for acute cardiogenic shock. During venoarterial (VA) ECMO support, left heart decompression should be considered when left ventricular (LV) distension develops with pulmonary edema and LV dysfunction. The aim of this study was to report the results of transaortic catheter venting (TACV), as an alternative venting method, performed during VA-ECMO in patients with acute cardiogenic shock. We retrospectively reviewed the records of seven patients who underwent both ECMO and TACV between February 2013 and February 2014. Extracorporeal membrane oxygenation was performed uneventfully, and TACV was introduced under transthoracic echocardiographic guidance in all cases. Hemodynamic parameters, LV ejection fraction, and LV end-diastolic dimension (LVEDD) were measured 24 hours after initiating TACV in survivors. There were no procedure-related complications. Four of the seven patients (58%) survived. Transaortic catheter venting led to an increase in mean blood pressure in all patients (p = 0.050). There was a significant difference between pre- and post-TACV-LVEDD (59 ± 14 vs. 50 ± 12 mm, p = 0.044), with a 10-23% reduction in LVEDD in survivors. Transaortic catheter venting might be an acceptable alternative to venting procedures and useful for LV recovery during VA-ECMO in patients with severe LV dysfunction.

摘要

体外膜肺氧合(ECMO)已成为急性心源性休克常用的机械支持手段之一。在静脉-动脉(VA)ECMO支持期间,当出现左心室(LV)扩张伴肺水肿及LV功能障碍时,应考虑进行左心减压。本研究的目的是报告经主动脉导管排气(TACV)作为一种替代排气方法,在急性心源性休克患者VA-ECMO期间的应用结果。我们回顾性分析了2013年2月至2014年2月期间接受ECMO和TACV的7例患者的记录。所有患者均顺利进行了体外膜肺氧合,且均在经胸超声心动图引导下进行了TACV。对存活患者在启动TACV 24小时后测量血流动力学参数、LV射血分数和LV舒张末期内径(LVEDD)。未发生与操作相关的并发症。7例患者中有4例(58%)存活。经主动脉导管排气使所有患者的平均血压升高(p = 0.050)。TACV前后LVEDD有显著差异(59±14 vs. 50±12 mm,p = 0.044),存活患者的LVEDD降低了10% - 23%。经主动脉导管排气可能是一种可接受的排气方法替代方案,对严重LV功能障碍患者在VA-ECMO期间的LV恢复有益。

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