Hoffer Michael E, Szczupak Mikhaylo, Kiderman Alexander, Crawford James, Murphy Sara, Marshall Kathryn, Pelusso Constanza, Balaban Carey
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
University of Miami Sports Performance and Wellness Institute, Miami, Florida, United States of America.
PLoS One. 2016 Jan 4;11(1):e0146039. doi: 10.1371/journal.pone.0146039. eCollection 2016.
Mild Traumatic Brain Injury (mTBI) is a prominent public health issue. To date, subjective symptom complaints primarily dictate diagnostic and treatment approaches. As such, the description and qualification of these symptoms in the mTBI patient population is of great value. This manuscript describes the symptoms of mTBI patients as compared to controls in a larger study designed to examine the use of vestibular testing to diagnose mTBI. Five symptom clusters were identified: Post-Traumatic Headache/Migraine, Nausea, Emotional/Affective, Fatigue/Malaise, and Dizziness/Mild Cognitive Impairment. Our analysis indicates that individuals with mTBI have headache, dizziness, and cognitive dysfunction far out of proportion to those without mTBI. In addition, sleep disorders and emotional issues were significantly more common amongst mTBI patients than non-injured individuals. A simple set of questions inquiring about dizziness, headache, and cognitive issues may provide diagnostic accuracy. The consideration of other symptoms may be critical for providing prognostic value and treatment for best short-term outcomes or prevention of long-term complications.
轻度创伤性脑损伤（mTBI）是一个突出的公共卫生问题。迄今为止，主观症状主诉主要决定诊断和治疗方法。因此，在mTBI患者群体中对这些症状进行描述和鉴定具有重要价值。在一项旨在研究使用前庭测试诊断mTBI的大型研究中，本手稿描述了mTBI患者与对照组相比的症状。确定了五个症状群：创伤后头痛/偏头痛、恶心、情绪/情感、疲劳/不适以及头晕/轻度认知障碍。我们的分析表明，mTBI患者出现头痛、头晕和认知功能障碍的程度远高于非mTBI患者。此外，mTBI患者中睡眠障碍和情绪问题比未受伤个体更为常见。一组简单的询问头晕、头痛和认知问题的问题可能会提供诊断准确性。考虑其他症状对于提供预后价值以及为实现最佳短期结果或预防长期并发症进行治疗可能至关重要。
