Marino Andreana, Zengin Gokhan, Nostro Antonia, Ginestra Giovanna, Dugo Paola, Cacciola Francesco, Miceli Natalizia, Taviano Maria Fernanda, Filocamo Angela, Bisignano Giuseppe, Aktumsek Abdurrahman
a Department of Pharmaceutical Sciences and Health Products , University of Messina , Messina , Italy.
b Department of Biology , University of Selcuk , Konya , Turkey.
Nat Prod Res. 2016 Nov;30(22):2620-2623. doi: 10.1080/14786419.2015.1129330. Epub 2016 Jan 4.
The antimicrobial activity of acetone, methanol and aqueous extracts of Asphodeline anatolica E. Tuzlaci leaves was evaluated against American type culture collection, food and clinical isolates (Listeria monocytogenes and Staphylococcus aureus including methicillin-resistant strains-MRSA). Biofilm formation, toxicity and characterisation of the polyphenolic content were analysed. The acetone extract demonstrated a higher antibacterial activity against S. aureus including MRSA strains, L. monocytogenes and Pseudomonas aeruginosa than against other extracts. No effect was observed in biofilm formation. The extracts resulted non-toxic against Artemia salina Leach. The phytochemical screening of extracts indicated that they mainly contained six polyphenols identified as catechin 3-O-gallate, protocatechuic acid, diosmin, rutin, cirsimaritin and kaempferol glucoside. This study is the first report on antimicrobial activity and phenolic content of A. anatolica and contributes to enrich the literature data on the biological properties of this plant. A. anatolica leaves have a potential as source of natural antimicrobial compounds.
对土耳其绵枣儿（Asphodeline anatolica E. Tuzlaci）叶片的丙酮提取物、甲醇提取物和水提取物针对美国模式培养物集、食品和临床分离株（单核细胞增生李斯特菌和金黄色葡萄球菌，包括耐甲氧西林菌株-MRSA）的抗菌活性进行了评估。分析了生物膜形成、毒性以及多酚含量的特征。与其他提取物相比，丙酮提取物对包括MRSA菌株在内的金黄色葡萄球菌、单核细胞增生李斯特菌和铜绿假单胞菌表现出更高的抗菌活性。在生物膜形成方面未观察到影响。提取物对卤虫（Artemia salina Leach）无毒。提取物的植物化学筛选表明，它们主要含有六种多酚，分别鉴定为儿茶素3-O-没食子酸酯、原儿茶酸、香叶木苷、芦丁、橙皮素和山柰酚糖苷。本研究是关于土耳其绵枣儿抗菌活性和酚类含量的首次报道，有助于丰富关于该植物生物学特性的文献数据。土耳其绵枣儿叶片有作为天然抗菌化合物来源的潜力。
