Turker A U, Usta C
Department of Biology, Abant Izzet Baysal University, 14280 Bolu, Turkey.
Nat Prod Res. 2008 Jan 20;22(2):136-46. doi: 10.1080/14786410701591663.
Screening of antibacterial activity and toxicity of 22 aqueous plant extracts from 17 Turkish plants was conducted. Antibacterial activity was performed with six bacteria including Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus pyogenes, Staphylococcus aureus and Staphylococcus epidermidis. Extracts of Tussilago farfara leaves, Helichyrsum plicatum flowers, Solanum dulcamara aerial parts and Urtica dioica leaves gave the best inhibitory activity against S. pyogenes, S. aureus and S. epidermidis. Of the 22 plant extracts, 20 extracts displayed toxicity (LC50 was <1000 mg L(-1)) in the brine shrimp bioassay. For radish seed bioassay, two different determinations (root length and seed germination) were performed with a comparison between two concentrations (50,000 mg L(-1) and 10,000 mg L(-1)). At low concentration (10,000 mg L(-1)), S. dulcamara aerial parts and Primula vulgaris leaf extracts were observed to inhibit the root length more than the other plant extracts. Also, the most inhibitive plant extract for seed germination was obtained with S. dulcamara aerial parts.
对来自17种土耳其植物的22种水性植物提取物进行了抗菌活性和毒性筛选。采用包括大肠杆菌、铜绿假单胞菌、肺炎克雷伯菌、化脓性链球菌、金黄色葡萄球菌和表皮葡萄球菌在内的6种细菌进行抗菌活性测试。款冬叶提取物、皱叶蜡菊花朵提取物、龙葵地上部分提取物和荨麻叶提取物对化脓性链球菌、金黄色葡萄球菌和表皮葡萄球菌具有最佳抑制活性。在22种植物提取物中，有20种提取物在卤虫生物测定中表现出毒性（半数致死浓度<1000 mg L(-1)）。对于萝卜籽生物测定，在两种浓度（50,000 mg L(-1)和10,000 mg L(-1)）之间进行比较，进行了两种不同的测定（根长和种子发芽）。在低浓度（10,000 mg L(-1)）下，观察到龙葵地上部分提取物和报春叶提取物对根长的抑制作用比其他植物提取物更强。此外，对种子发芽抑制作用最强的植物提取物也是龙葵地上部分提取物。
