Marini John J, Gattinoni Luciano, Ince Can, Kozek-Langenecker Sibylle, Mehta Ravindra L, Pichard Claude, Westphal Martin, Wischmeyer Paul, Vincent Jean-Louis
Crit Care. 2015;19 Suppl 3(Suppl 3):S1. doi: 10.1186/cc14719. Epub 2015 Dec 18.
Medical practice is rooted in our dependence on the best available evidence from incremental scientific experimentation and rigorous clinical trials. Progress toward determining the true worth of ongoing practice or suggested innovations can be glacially slow when we insist on following the stepwise scientific pathway, and a prevailing but imperfect paradigm often proves difficult to challenge. Yet most experienced clinicians and clinical scientists harbor strong thoughts about how care could or should be improved, even if the existing evidence base is thin or lacking. One of our Future of Critical Care Medicine conference sessions encouraged sharing of novel ideas, each presented with what the speaker considers a defensible rationale. Our intent was to stimulate insightful thinking and free interchange, and perhaps to point in new directions toward lines of innovative theory and improved care of the critically ill. In what follows, a brief background outlines the rationale for each novel and deliberately provocative unconfirmed idea endorsed by the presenter.
医学实践植根于我们对来自渐进性科学实验和严格临床试验的最佳现有证据的依赖。当我们坚持遵循逐步的科学路径时，确定现行实践或建议创新的真正价值的进展可能极其缓慢，而且一种普遍但并不完美的范式往往难以挑战。然而，即使现有的证据基础薄弱或缺乏，大多数经验丰富的临床医生和临床科学家对于如何改进护理也有着强烈的想法。我们的危重病医学未来会议的一场会议鼓励分享新颖的想法，每个想法都由演讲者提出其认为合理的依据。我们的目的是激发深刻的思考和自由交流，或许还能为创新理论和改善危重病护理指明新的方向。以下内容简要介绍了演讲者认可的每个新颖且刻意具有启发性的未经证实想法的依据。
