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酷似肝母细胞瘤的间叶性错构瘤:细胞学诊断陷阱

Mesenchymal hamartoma mimicking hepatoblastoma: A cytological pitfall.

作者信息

Verma Deepti, Agarwal Shilpi, Puri Vandana, Singh Deeksha, Bundela Tanuja

机构信息

Department of Pathology, Lady Hardinge Medical College, New Delhi, India.

出版信息

J Cytol. 2015 Jul-Sep;32(3):197-200. doi: 10.4103/0970-9371.168903.

DOI:10.4103/0970-9371.168903
PMID:26729984
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4687214/
Abstract

The case of a 9-month-old infant who presented with an abdominal mass since birth is discussed here. Fine-needle aspiration (FNA) cytology of this mass was performed, from which it was thought to be a small round tumor, possibly a hepatoblastoma (HB). Histopathologically, however, it was found to be a mesenchymal hamartoma (MH). This case report thus highlights this cytological limitation.

摘要

本文讨论了一名自出生以来即出现腹部肿块的9个月大婴儿的病例。对该肿块进行了细针穿刺(FNA)细胞学检查,据此认为它是一个小圆细胞瘤,可能是肝母细胞瘤(HB)。然而,组织病理学检查发现它是间叶性错构瘤(MH)。因此,本病例报告突出了这种细胞学检查的局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/5803ccaa6584/JCytol-32-197-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/b1c00068eb2e/JCytol-32-197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/bf49213fecbd/JCytol-32-197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/5803ccaa6584/JCytol-32-197-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/b1c00068eb2e/JCytol-32-197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/bf49213fecbd/JCytol-32-197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0347/4687214/5803ccaa6584/JCytol-32-197-g003.jpg

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本文引用的文献

1
From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation. Part 2. Malignant tumors.从 AFIP 档案中:儿科肝脏肿块:放射学-病理学相关性。第 2 部分。恶性肿瘤。
Radiographics. 2011 Mar-Apr;31(2):483-507. doi: 10.1148/rg.312105201.
2
Mesenchymal hamartoma of the liver mimicking hepatoblastoma.酷似肝母细胞瘤的肝脏间叶性错构瘤
J Pediatr Hematol Oncol. 2008 Jun;30(6):458-60. doi: 10.1097/MPH.0b013e318169171b.
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Hepatic mesenchymal hamartoma: a short review.肝间叶性错构瘤:简要综述
Arch Pathol Lab Med. 2006 Oct;130(10):1567-9. doi: 10.5858/2006-130-1567-HMHASR.
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Mesenchymal hamartomas of the liver may be associated with increased serum alpha foetoprotein concentrations and mimic hepatoblastomas.肝脏间叶性错构瘤可能与血清甲胎蛋白浓度升高有关,并酷似肝母细胞瘤。
Eur J Pediatr Surg. 2004 Feb;14(1):63-6. doi: 10.1055/s-2004-815784.
5
Small cells in hepatoblastoma lack "oval" cell phenotype.肝母细胞瘤中的小细胞缺乏“卵圆”细胞表型。
Mod Pathol. 2003 Sep;16(9):930-6. doi: 10.1097/01.MP.0000086486.52370.81.
6
Fine needle aspiration cytology of mesenchymal hamartoma of the liver. A case report.肝脏间叶性错构瘤的细针穿刺抽吸细胞学检查。病例报告。
Acta Cytol. 2000 May-Jun;44(3):449-53. doi: 10.1159/000328497.
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Fine needle aspiration cytology of undifferentiated (embryonal) sarcoma of the liver. A case report.
Acta Cytol. 1997 Jul-Aug;41(4 Suppl):1273-8. doi: 10.1159/000333519.