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Synthesis of some thiazoline and thiazolidinone derivatives of 1,4-benzoquinone as potential antimicrobial agents.

作者信息

el-Khawass S M, Khalil M A, Chaaban I

机构信息

Pharmaceutical Chemistry Department, Faculty of Pharmacy, University of Alexandria, Egypt.

出版信息

Farmaco. 1989 Apr;44(4):415-21. doi: 10.1002/chin.198947193.

DOI:10.1002/chin.198947193
PMID:2673262
Abstract

Three novel series of benzoquinone derivatives were synthesized, namely: N-(3-aryl-4-phenylthiazolin-2-ylidene)-N-(1,4-benzoquinone carbonyl) hydrazines; N-(3-aryl-5-carbethoxy-4-methylthiazolin-2-ylidene)-N-(1,4- benzoquinone carbonyl)hydrazine and N-(3-arylthiazolin-4-one-2-ylidene)-N-(1,4- benzoquinone carbonyl) hydrazines. These series were prepared by oxidation of the new hydroquinone precursors. The antimicrobial activity of representative compounds of benzoquinone, as well as of hydroquinone derivatives was studied.

摘要

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