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腹腔镜D2加完整胃系膜切除术采用“愉悦空间”入路与传统D2全胃切除术治疗局部进展期胃癌的短期疗效

Laparoscopic D2 plus complete mesogastrium excision using the "enjoyable space" approach versus conventional D2 total gastrectomy for local advanced gastric cancer: short-term outcomes.

作者信息

Zheng Chang-Yue, Dong Zhi-Yong, Zheng Long-Zhi, Qiu Xian-Tu, Zu Bin, Xu Rui, Lin Wei

机构信息

Department of Gastrointestinal Surgery, the Affiliated Hospital of Putian University, Putian, Fujian Province, China.

Gastrointestinal Surgery Research Institute, the Affiliated Hospital of Putian University, Putian, Fujian Province, China.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2020 Mar;15(1):58-69. doi: 10.5114/wiitm.2019.85540. Epub 2019 May 29.

DOI:10.5114/wiitm.2019.85540
PMID:32117487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7020705/
Abstract

INTRODUCTION

Laparoscopy-assisted radical total gastrectomy is technically demanding.

AIM

To introduce the "enjoyable space" approach to achieve D2 plus complete mesogastrium excision (CME) and to investigate its safety and feasibility.

MATERIAL AND METHODS

Between January 2015 and December 2017, 165 patients with primary advanced upper gastric cancer underwent laparoscopy-assisted radical total gastrectomy. Among these patients, 81 underwent conventional D2 total gastrectomy (D2 group) and 84 underwent D2 plus CME total gastrectomy (D2 + CME group). Clinicopathological characteristics, surgical outcomes and postoperative complications were compared between the two groups.

RESULTS

There were no significant differences between the two groups (p > 0.05) in clinicopathological characteristics. However, the D2 + CME group had a longer mean operative time, lower mean blood loss and slightly higher mean number of retrieved lymph nodes (LNs) than the D2 group (p < 0.05 each). The mean time to first flatus, liquid diet, and soft diet and the duration of hospital stay were similar between the two groups (p > 0.05 each). No significant difference in postoperative complication rates was found between the groups (16.0% vs. 9.5%, p > 0.05).

CONCLUSIONS

The "enjoyable space" approach is an option to achieve D2 + CME, and its safety and feasibility over conventional method are confirmed with lower intraoperative blood loss and more harvested LNs.

摘要

引言

腹腔镜辅助根治性全胃切除术技术要求较高。

目的

介绍“舒适空间”手术方法以实现D2根治术加完整胃系膜切除(CME),并探讨其安全性和可行性。

材料与方法

2015年1月至2017年12月,165例原发性进展期近端胃癌患者接受了腹腔镜辅助根治性全胃切除术。其中,81例行传统D2全胃切除术(D2组),84例行D2加CME全胃切除术(D2 + CME组)。比较两组患者的临床病理特征、手术结果及术后并发症。

结果

两组患者的临床病理特征无显著差异(p > 0.05)。然而,D2 + CME组的平均手术时间更长,平均失血量更低,平均获取淋巴结(LN)数量略高于D2组(各p < 0.05)。两组患者首次排气、流食、软食的平均时间及住院时间相似(各p > 0.05)。两组术后并发症发生率无显著差异(16.0% 对9.5%,p > 0.05)。

结论

“舒适空间”手术方法是实现D2 + CME的一种选择,其相对于传统方法的安全性和可行性得到证实,术中失血量更少,获取的LN更多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/84178c76dd5f/WIITM-15-36813-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/b9061daa35f1/WIITM-15-36813-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/45606a241f18/WIITM-15-36813-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/84178c76dd5f/WIITM-15-36813-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/b9061daa35f1/WIITM-15-36813-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/8eb6090b1dea/WIITM-15-36813-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/3728adade03f/WIITM-15-36813-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/8c495f1921c6/WIITM-15-36813-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a03e/7020705/45606a241f18/WIITM-15-36813-g005.jpg
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