揭示体内炎性小体活性。
Illuminating inflammasome activity in vivo.
作者信息
Hickman Heather D
机构信息
Laboratory of Viral Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
出版信息
Nat Med. 2016 Jan;22(1):22-3. doi: 10.1038/nm.4026.
Abstract
Sentinel macrophages in the lymph node provide a first line of defense against invading viruses. A new study visualizes inflammasome activation in virally infected nodal macrophages in mice and shows that this activation augments both innate and adaptive immunity.
摘要
淋巴结中的哨兵巨噬细胞为抵御入侵病毒提供了第一道防线。一项新研究观察到了小鼠病毒感染的淋巴结巨噬细胞中的炎性小体激活，并表明这种激活增强了先天性免疫和适应性免疫。
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