Marcus R
Aging Study Unit, Veterans Administration Medical Center, Palo Alto, California.
Endocrinol Metab Clin North Am. 1989 Sep;18(3):715-22.
Although surgery remains the only curative treatment for primary hyperparathyroidism, interest continues in developing alternative therapy for patients who reject or cannot undergo an operation. For the majority of patients (who are menopausal women), estrogen or progestin therapy may control hypercalcemia and calciuria and reduce the rate of bone turnover. Whether the long-term clinical outcome of hyperparathyroidism is improved by hormone replacement remains to be established.
虽然手术仍然是原发性甲状旁腺功能亢进的唯一治愈性治疗方法，但对于拒绝手术或无法接受手术的患者，开发替代疗法的兴趣依然存在。对于大多数患者（绝经后女性）而言，雌激素或孕激素疗法可能控制高钙血症和高钙尿症，并降低骨转换率。激素替代疗法是否能改善甲状旁腺功能亢进的长期临床结局仍有待确定。
