基于苝-3,4,9,10-四羧酸四酯的荧光正电子发射断层扫描（PET）探针。
Fluorescent PET probes based on perylene-3,4,9,10-tetracarboxylic tetraesters.
作者信息
Dubey Rajeev K, Knorr Gergely, Westerveld Nick, Jager Wolter F
机构信息
Department of Chemical Engineering, Delft University of Technology, Julianalaan 136, 2628BL Delft, The Netherlands.
Institute of Organic Chemistry, Hungarian Academy of Sciences, 1519 Budapest, PO Box 286, Hungary.
出版信息
Org Biomol Chem. 2016 Feb 7;14(5):1564-8. doi: 10.1039/c5ob02540k.
Perylene-3,4,9,10-tetracarboxylic tetraester-based fluorescent PET probes with aniline receptors attached either at the peri- or the bay-positions have been synthesized. By attaching aniline receptors at the bay position, pH-sensitive "light-up" probes, with fluorescence quantum yields ΦF > 0.75 and fluorescent enhancements FE > 500 in ethanol, have been obtained.
已经合成了在苝-3,4,9,10-四羧酸四酯荧光PET探针的周边或湾区连接苯胺受体的化合物。通过在湾区连接苯胺受体，得到了对pH敏感的“点亮”型探针，其在乙醇中的荧光量子产率ΦF>0.75，荧光增强FE>500。
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