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通过上消化道内镜观察到的严重发热伴血小板减少综合征患者的出血性溃疡性病变

Ulcerative Lesions with Hemorrhage in a Patient with Severe Fever with Thrombocytopenia Syndrome Observed via Upper Gastrointestinal Endoscopy.

作者信息

Kaneyuki Shozo, Yoshikawa Tomoki, Tani Hideki, Fukushi Shuetsu, Taniguchi Satoshi, Fukuma Aiko, Shimojima Masayuki, Kurosu Takeshi, Morikawa Shigeru, Saijo Masayuki

机构信息

Department of Internal Medicine, Dohi Hospital.

出版信息

Jpn J Infect Dis. 2016 Nov 22;69(6):525-527. doi: 10.7883/yoken.JJID.2015.404. Epub 2016 Jan 8.

DOI:10.7883/yoken.JJID.2015.404
PMID:26743149
Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is a novel bunyavirus infection caused by the SFTS virus (SFTSV, family Bunyaviridae, genus Phlebovirus) with a high case fatality rate. A previously healthy 72-year-old man showed symptoms of fever, general fatigue, and altered consciousness. He was hospitalized for treatment. On day 3, considering the day on which fever appeared first during the disease course as day 0, he had bloody emesis. An emergency upper gastrointestinal endoscopic examination revealed multiple ulcerative lesions with continuously oozing hemorrhage in the stomach. He died on day 7. He was retrospectively diagnosed as having SFTS, Although it was less likely that the gastric ulcerative lesions were directly induced by SFTSV replication, it was evident that hemorrhagic emesis might occur in the patient in association with the pathophysiology of SFTS. The real-time imaging of gastric ulcerative lesions in a patient with SFTS is reported.

摘要

严重发热伴血小板减少综合征(SFTS)是一种由SFTS病毒(SFTSV,布尼亚病毒科白蛉病毒属)引起的新型布尼亚病毒感染,病死率很高。一名既往健康的72岁男性出现发热、全身乏力和意识改变症状。他住院接受治疗。在病程中,以首次发热日为第0天,第3天时他出现呕血。急诊上消化道内镜检查发现胃内有多个溃疡性病变,伴有持续渗血。他于第7天死亡。回顾性诊断他患有SFTS。虽然胃溃疡性病变不太可能由SFTSV复制直接引起,但显然该患者可能会因SFTS的病理生理机制而发生呕血。本文报道了一例SFTS患者胃溃疡性病变的实时成像情况。

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