Marchetti C, Chierego G, Pozza F
Servizio di Fisica Sanitaria, Centro di Radiochirurgia della Regione Veneto, U.S.L. n. 8, Vicenza, Italy.
J Neurosurg Sci. 1989 Jan-Mar;33(1):127-30.
The authors have reviewed their experience with treatments of small intracranial lesions by unconventionally fractionated stereotactic radiotherapy using a 4 MV photon beam. Treatment is carried out by multiple non coplanar arc irradiation obtained rotating the target, while kept at the isocentre of a Linac, around a vertical axis. The outmost concentration of the dose within the target volume enables consistent reduction of the amount of the absorbed dose by critical structures of the intact brain. They analyse the dose distribution and the method to optimise the choice of the therapeutic dose. Finally, some radiobiological considerations are presented.
作者回顾了他们使用4MV光子束通过非常规分割立体定向放射疗法治疗颅内小病变的经验。治疗通过在直线加速器的等中心将靶区围绕垂直轴旋转进行多个非共面弧形照射来实施。靶区内剂量的最高集中能够持续减少完整脑组织关键结构的吸收剂量。他们分析了剂量分布以及优化治疗剂量选择的方法。最后，提出了一些放射生物学方面的考虑。
