Yamaguchi K, Hayasaka S, Hara S, Kurobane I, Tada K
Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan.
Ophthalmic Res. 1989;21(3):226-9. doi: 10.1159/000266812.
We examined the lysosomal enzyme levels in tear fluids from a patient with I-cell disease after treatment by bone marrow transplantation. Acid phosphatase, beta-D-glucuronidase, N-acetyl-beta-D-glucosaminidase, alpha-L-fucosidase and alpha-D-mannosidase activities were reduced to normal or nearly normal levels after the treatment. We believe that the measurement of tear enzyme levels in I-cell disease is useful for knowing the efficacy of the bone marrow transplantation.
我们检测了一名患有I-细胞病的患者在接受骨髓移植治疗后泪液中的溶酶体酶水平。治疗后，酸性磷酸酶、β-D-葡萄糖醛酸酶、N-乙酰-β-D-氨基葡萄糖苷酶、α-L-岩藻糖苷酶和α-D-甘露糖苷酶的活性降至正常或接近正常水平。我们认为，检测I-细胞病患者泪液中的酶水平有助于了解骨髓移植的疗效。
