Yakin Muhammed, Jalal Jalal A, Al-Khurri Luay E, Rich Alison M
Faculty of Dentistry, Sir John Walsh Research Institute, University of Otago, Dunedin, New Zealand.
Department of Pathology, College of Medicine, Hawler Medical University, Erbil, Iraq.
Int Dent J. 2016 Apr;66(2):78-85. doi: 10.1111/idj.12211. Epub 2016 Jan 7.
The majority of surveys concerning oral pathology accessions have focused on specific pathological categories or particular age groups, and few studies have analysed the whole range of specimens submitted for histopathological examination. An analysis of all oral pathology submitted to the Department of Histopathology in Rizgary Teaching Hospital in Erbil, Iraq, during the 6-year period 2008-2013, was performed.
Histopathology samples (excluding smears) from the maxillae, mandible, salivary glands, the lips and oral mucosa, the tongue, the hard and soft palate and uvula, and the pillars of the fauces were included. The specimens were grouped into six diagnostic categories: oral mucosal and skin pathology; benign neoplasms; malignant neoplasms; non-neoplastic salivary gland disorders; cysts; and miscellaneous pathology.
The total number of oral and maxillofacial specimens was 616 of 20,571 specimens. One-third of the oral and maxillofacial specimens were in the mucosal and skin pathology category, followed by benign neoplasms (24.2%) - of which 26.8% were odontogenic tumours and 42.6% were salivary gland tumours - and malignant neoplasms (n = 100, 16.2%). Neoplastic (n = 62) and non-neoplastic (n = 41) salivary gland disorders accounted for 16.7% (n = 103) of the specimens submitted, whereas odontogenic cysts (n = 34) and tumours (n = 40) comprised 5.5% and 6.5% of all biopsies.
Many of our findings are consistent with those reported in the literature. However, a relatively larger proportion of neoplastic lesions were found in our cohort and in other Iraqi centres. Of concern to practising clinicians in Iraq is that one in 10 biopsies submitted was a squamous cell carcinoma and three in 20 accessions were malignant.
大多数关于口腔病理学病例的调查都集中在特定的病理类别或特定年龄组，很少有研究分析提交进行组织病理学检查的所有标本。对2008年至2013年6年间提交给伊拉克埃尔比勒里兹加里教学医院组织病理学系的所有口腔病理学标本进行了分析。
纳入来自上颌骨、下颌骨、唾液腺、嘴唇和口腔黏膜、舌头、硬腭和软腭及悬雍垂以及咽弓的组织病理学样本（不包括涂片）。标本分为六个诊断类别：口腔黏膜和皮肤病理学；良性肿瘤；恶性肿瘤；非肿瘤性唾液腺疾病；囊肿；以及其他病理学。
口腔颌面标本总数为20571份标本中的616份。三分之一的口腔颌面标本属于黏膜和皮肤病理学类别，其次是良性肿瘤（24.2%），其中26.8%为牙源性肿瘤，42.6%为唾液腺肿瘤，恶性肿瘤（n = 100，16.2%）。肿瘤性（n = 62）和非肿瘤性（n = 41）唾液腺疾病占提交标本的16.7%（n = 103），而牙源性囊肿（n = 34）和肿瘤（n = 40）分别占所有活检的5.5%和6.5%。
我们的许多发现与文献报道一致。然而，在我们的队列和其他伊拉克中心发现的肿瘤性病变比例相对较大。伊拉克临床医生关注的是，提交的活检标本中有十分之一是鳞状细胞癌，每20份标本中有三份是恶性的。
