Radchatawedchakoon Widchaya, Bamrungsuk Suthep, Namwijit Siriporn, Apiratikul Nuttapon, Sakee Uthai, Yingyongnarongkul Boon-ek
Nat Prod Commun. 2015 Nov;10(11):1973-5.
One new furanocoumarin, 3'-prenyloxypsoralen (1), and two known furanocoumarins, imperatorin (2) and xanthotoxin (3) were isolated from the raw fruits of Aegle marmelos. The structures of the isolated coumarins were confirmed by spectroscopic evidence. Compound 1 exhibited moderate cytotoxic activity against HEK293, HeLa, MCF7, and HT29 cell lines with IC50 values of 31.2, 44.8, 36.3, and > 50.0 µg/mL, respectively.
从印度枳椇的未成熟果实中分离出一种新的呋喃香豆素3'-异戊烯氧基补骨脂素（1）以及两种已知的呋喃香豆素欧前胡素（2）和花椒毒素（3）。通过光谱学证据确定了分离得到的香豆素的结构。化合物1对HEK293、HeLa、MCF7和HT29细胞系表现出中等细胞毒性活性，IC50值分别为31.2、44.8、36.3和>50.0μg/mL。
