Behr C, Goltzene M A, Kosmalski G, Hirsch E, Ryvlin P
Department of neurology, university hospital of Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.
Department of neurology, university hospital of Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.
Rev Neurol (Paris). 2016 Jan;172(1):27-36. doi: 10.1016/j.neurol.2015.11.003. Epub 2016 Jan 2.
Epilepsy is a burden affecting no fewer than 50 million patients worldwide. It is a heterogeneous group of disorders comprising both common and very rare forms, thus rendering its epidemiological investigations rather difficult. Moreover, making an epilepsy diagnosis per se can be challenging due to an evolving system of classification, and its dependency on local habits and culture. Any attempt at meta-analyses must consider such biases when pooling data from different centers and countries. Differentiating a contextual seizure from chronic epilepsy is every epileptologist's daily mission, yet it is also crucial for achieving a proper estimation of the epidemiology of epilepsy. Our present objective was to provide an overview of the epidemiology of both syndromic and non-syndromic epilepsy. Most epileptic syndromes tend to be rare and, thus, the feasibility of epidemiological quantification in populations is also addressed. Regarding its prevalence and cost, epilepsy deserves greater attention than it generally receives, as it appears to continue to be a condition under persistent taboos.
癫痫是一种负担，全球受其影响的患者不少于5000万。它是一组异质性疾病，包括常见和非常罕见的形式，因此其流行病学调查相当困难。此外，由于分类系统不断演变，且依赖于当地习惯和文化，癫痫诊断本身可能具有挑战性。在对来自不同中心和国家的数据进行汇总时，任何荟萃分析的尝试都必须考虑到此类偏差。区分情境性发作和慢性癫痫是每位癫痫学家的日常任务，但对于准确估计癫痫的流行病学也至关重要。我们目前的目标是概述症状性和非症状性癫痫的流行病学。大多数癫痫综合征往往较为罕见，因此还讨论了在人群中进行流行病学量化的可行性。就其患病率和成本而言，癫痫应得到比通常更多的关注，因为它似乎仍然是一种长期受到禁忌的疾病。
