Campos-Magdaleno María, Facal David, Juncos-Rabadán Onésimo, Picón Eduardo, Pereiro Arturo Xosé
University of Santiago de Compostela, Spain
University of Santiago de Compostela, Spain.
J Aging Health. 2016 Sep;28(6):1105-15. doi: 10.1177/0898264315624908. Epub 2016 Jan 10.
The aim of this study is to compare an empirically derived classification of amnestic mild cognitive impairment (aMCI) from a sample of adults with subjective cognitive complaints by using cluster analysis of their performance on the California Verbal Learning Test (CVLT) with a classification of aMCI based on standard clinical criteria.
Three hundred ninety-one individuals aged 48 years and older were diagnosed as aMCI or healthy controls. Cluster analysis of the CVLT performance was conducted, followed by logistic regression analysis.
A two-cluster solution performed on the CVLT measures correctly classified 98.0% of the aMCI patients and 73.4% of the healthy controls diagnosed by using standard aMCI criteria.
The empirically derived classification of aMCI is consistent with the classification based on standard criteria; however, standard criteria should also be considered to prevent false positives.
本研究旨在通过对加利福尼亚言语学习测验（CVLT）成绩进行聚类分析，将一组有主观认知主诉的成年人样本中根据经验得出的遗忘型轻度认知障碍（aMCI）分类，与基于标准临床标准的aMCI分类进行比较。
391名48岁及以上的个体被诊断为aMCI或健康对照。对CVLT成绩进行聚类分析，随后进行逻辑回归分析。
对CVLT测量结果进行的双聚类分析正确分类了98.0%的aMCI患者和73.4%使用标准aMCI标准诊断的健康对照。
根据经验得出的aMCI分类与基于标准标准的分类一致；然而，也应考虑标准标准以防止假阳性。
