Sarquis Leila M M, Coggon David, Ntani Georgia, Walker-Bone Karen, Palmer Keith T, Felli Vanda E, Harari Raul, Barrero Lope H, Felknor Sarah A, Gimeno David, Cattrell Anna, Vargas-Prada Sergio, Bonzini Matteo, Solidaki Eleni, Merisalu Eda, Habib Rima R, Sadeghian Farideh, Kadir M Masood, Warnakulasuriya Sudath S P, Matsudaira Ko, Nyantumbu Busisiwe, Sim Malcolm R, Harcombe Helen, Cox Ken, Marziale Maria H, Harari Florencia, Freire Rocio, Harari Natalia, Monroy Magda V, Quintana Leonardo A, Rojas Marianela, Harris E Clare, Serra Consol, Martinez J Miguel, Delclos George, Benavides Fernando G, Carugno Michele, Ferrario Marco M, Pesatori Angela C, Chatzi Leda, Bitsios Panos, Kogevinas Manolis, Oha Kristel, Freimann Tiina, Sadeghian Ali, Peiris-John Roshini J, Sathiakumar Nalini, Wickremasinghe A Rajitha, Yoshimura Noriko, Kelsall Helen L, Hoe Victor C W, Urquhart Donna M, Derrett Sarah, McBride David, Herbison Peter, Gray Andrew, Salazar Vega Eduardo J
Federal University of Paraná, Curitiba-PR, Brazil Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom Arthritis Research UK/MRC Centre for Musculoskeletal Health and Work, University of Southampton, Southampton, United Kingdom School of Nursing, University of São Paulo, São Paulo, Brazil Corporación para el Desarrollo de la Producción y el Medio Ambiente Laboral-IFA (Institute for the Development of Production and the Work Environment), Quito, Ecuador Department of Industrial Engineering, School of Engineering, Pontificia Universidad Javeriana, Bogotá, Colombia Southwest Center for Occupational and Environmental Health, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA Center for Disease Control and Prevention/National Institute for Occupational Safety and Health, Atlanta, GA, USA Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry Psychology and Neuroscience, Kings College London, London, United Kingdom Center for Research in Occupational Health (CiSAL), Universitat Pompeu Fabra, Barcelona, Spain CIBER of Epidemiology and Public Health, Barcelona, Spain IMIM (Hospital del Mar Research Institute), Barcelona, Spain Epidemiology and Preventive Medicine Research Center, University of Insubria, Varese, Italy Department of Social Medicine, Medical School, University of Crete, Heraklion, Greece Institute of Technology, Estonian University of Life Sciences, Tartu, Estonia Department of Environmental Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon Department of Occupational Health, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan Department of Medical Education and Health Sciences, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka Department for Medical Research and Management for Musculoskeletal Pain, 22nd Century Medical and Research Center, Faculty of Medicine, The University of Tokyo Hospital, Tokyo, Japan National Institute for Occupational Health, National Health Laboratory Service, Johannesburg, South Africa Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand School of Nursing of Ribeirão Preto, University of São Paulo, São Paulo, Brazil Program Health, Work and Environment in Central America, Institute for Studies on Toxic Substances (IRET), National University of Costa Rica, Heredia, Costa Rica Occupational Health Service, Parc de Salut MAR, Barcelona, Spain Servicio de Investigación y Análisis IT/EP, Departamento de Investigación y Análisis de Prestaciones, MC Mutual, Barcelona, Spain Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy Department of Psychiatry, Medical School, University of Crete, Heraklion, Greece Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain North Estonia Medical Centre, Tallinn, Estonia Tartu University Hospital, Tartu, Estonia Klinikum Leverkusen, Leverkusen, Germany Department of Physiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka Section of Epidemiology and Biostatistics, School of Population Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka Department of Joint Disease Research, 22nd Century Medical and Research Center, University of Tokyo, Tokyo, Japan Centre for Occupational and Environmental Health, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Injury Prevention Research Unit, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand AkzoNobel, Houston, TX, USA.
Pain. 2016 May;157(5):1028-1036. doi: 10.1097/j.pain.0000000000000477.
To inform case definition for neck/shoulder pain in epidemiological research, we compared levels of disability, patterns of association, and prognosis for pain that was limited to the neck or shoulders (LNSP) and more generalised musculoskeletal pain that involved the neck or shoulder(s) (GPNS). Baseline data on musculoskeletal pain, disability, and potential correlates were collected by questionnaire from 12,195 workers in 47 occupational groups (mostly office workers, nurses, and manual workers) in 18 countries (response rate = 70%). Continuing pain after a mean interval of 14 months was ascertained through a follow-up questionnaire in 9150 workers from 45 occupational groups. Associations with personal and occupational factors were assessed by Poisson regression and summarised by prevalence rate ratios (PRRs). The 1-month prevalence of GPNS at baseline was much greater than that of LNSP (35.1% vs 5.6%), and it tended to be more troublesome and disabling. Unlike LNSP, the prevalence of GPNS increased with age. Moreover, it showed significantly stronger associations with somatising tendency (PRR 1.6 vs 1.3) and poor mental health (PRR 1.3 vs 1.1); greater variation between the occupational groups studied (prevalence ranging from 0% to 67.6%) that correlated poorly with the variation in LNSP; and was more persistent at follow-up (72.1% vs 61.7%). Our findings highlight important epidemiological distinctions between subcategories of neck/shoulder pain. In future epidemiological research that bases case definitions on symptoms, it would be useful to distinguish pain that is localised to the neck or shoulder from more generalised pain that happens to involve the neck/shoulder region.
为了明确流行病学研究中颈部/肩部疼痛的病例定义,我们比较了局限于颈部或肩部的疼痛(LNSP)和涉及颈部或肩部的更广泛的肌肉骨骼疼痛(GPNS)的残疾程度、关联模式和预后。通过问卷调查收集了来自18个国家47个职业群体(主要是办公室职员、护士和体力劳动者)的12195名工人的肌肉骨骼疼痛、残疾及潜在相关因素的基线数据(回复率 = 70%)。通过对来自45个职业群体的9150名工人进行随访问卷调查,确定了平均间隔14个月后的持续性疼痛。通过泊松回归评估与个人和职业因素的关联,并以患病率比(PRRs)进行总结。基线时GPNS的1个月患病率远高于LNSP(35.1%对5.6%),且往往更麻烦、致残性更强。与LNSP不同,GPNS的患病率随年龄增加。此外,它与躯体化倾向(PRR 1.6对1.3)和心理健康不佳(PRR 1.3对1.1)的关联显著更强;所研究职业群体之间的差异更大(患病率从0%到67.6%),且与LNSP的差异相关性较差;在随访中更持续(72.1%对61.7%)。我们的研究结果突出了颈部/肩部疼痛亚类之间重要的流行病学差异。在未来基于症状进行病例定义的流行病学研究中,区分局限于颈部或肩部的疼痛与碰巧涉及颈部/肩部区域的更广泛疼痛将是有用的。