Lang P G
Department of Dermatology and Otolaryngology, Medical University of South Carolina, Charleston.
Dermatol Clin. 1989 Oct;7(4):613-26.
Because of its superior histologic control, when compared with conventional surgery, Mohs micrographic surgery offers 5-year cure rates of 98 to 99% when dealing with aggressive, extensive, and/or recurrent cutaneous neoplasms. Because the fresh-tissue technique is faster, less painful, and more tissue conserving, allows for immediate repairs, yields higher quality histologic preparations, and facilitates an interdisciplinary approach, it has become the preferred method of performing Mohs micrographic surgery. The fixed-tissue technique does offer certain advantages when dealing with (1) vascular neoplasms or tumors in vascular areas; (2) tumor in deep, narrow spaces; (3) tumor invading bone; or (4) tumors capable of implantation and metastatic spread. However, a modification of the fresh-tissue technique, the use of the CO2 laser, or an interdisciplinary approach may also allow the Mohs surgeon to effectively deal with these problem cases.
与传统手术相比，莫氏显微描记手术具有卓越的组织学控制效果。在处理侵袭性、广泛性和/或复发性皮肤肿瘤时，其5年治愈率为98%至99%。由于新鲜组织技术速度更快、疼痛更少、更能保留组织、允许即时修复、能产生更高质量的组织学标本并便于采用多学科方法，它已成为进行莫氏显微描记手术的首选方法。在处理（1）血管性肿瘤或血管区域的肿瘤；（2）深部狭窄空间的肿瘤；（3）侵犯骨骼的肿瘤；或（4）能够种植和转移扩散的肿瘤时，固定组织技术确实具有某些优势。然而，对新鲜组织技术进行改良、使用二氧化碳激光或采用多学科方法，也可能使莫氏外科医生有效地处理这些疑难病例。
