Şahan Berna, Çiftçi Ferda, Özkan Ferda, Öztürk Vildan
Yeditepe University Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey.
Yeditepe University Faculty of Medicine, Department of Pathology, İstanbul, Turkey.
Turk J Ophthalmol. 2016 Dec;46(6):277-281. doi: 10.4274/tjo.48640. Epub 2016 Dec 1.
To show the importance of frozen section-controlled excision to avoid the re-recurrence of recurrent basal cell carcinoma (BCC) of the eyelids.
Thirty-five cases who underwent eyelid tumor excision in different centers and were admitted to our clinic with recurrent eyelid tumors. Recurrent tumors were resected by excision 1-2 mm from the tumor's visible margin and sent to pathology for frozen section examination. Eyelid reconstructions with flap and graft were performed after confirming that the surgical margins were negative.
Twenty-one (60%) of our patients were male and 14 (40%) were female. Median age of our group was 63.4±14.2 years. Excision and sending the excised material for frozen section control was performed once for 11 patients, twice for 12 patients, 3 times for 8 patients and 4 times for 4 patients to confirm that the surgical margins were clean. All pathology samples were reported as BCC. All patients had eyelid reconstruction with flap and graft. Recurrence was detected in 2 patients (5.7%) during 1 to 8 years (mean 4.3 years) of follow-up and those patients were reoperated; no recurrence was detected in the remaining 33 patients (94.3%).
Frozen section control can provide low re-recurrence rate in patients with recurrent BCC of the eyelids.
显示冰冻切片控制下切除对于避免眼睑复发性基底细胞癌（BCC）再次复发的重要性。
35例在不同中心接受眼睑肿瘤切除且因复发性眼睑肿瘤入住我院的患者。复发性肿瘤从肿瘤可见边缘向外1 - 2毫米处切除，送检病理进行冰冻切片检查。确认手术切缘阴性后，采用皮瓣和植皮进行眼睑重建。
我们的患者中21例（60%）为男性，14例（40%）为女性。本组患者的中位年龄为63.4±14.2岁。11例患者切除并送检切除组织进行冰冻切片检查1次，12例患者检查2次，8例患者检查3次，4例患者检查4次以确认手术切缘干净。所有病理样本报告均为基底细胞癌。所有患者均采用皮瓣和植皮进行眼睑重建。在1至8年（平均4.3年）的随访期间，2例患者（5.7%）出现复发并再次手术；其余33例患者（94.3%）未检测到复发。
冰冻切片控制可使眼睑复发性基底细胞癌患者的再次复发率较低。
