Luo Yi-Yuan, Liu Juan-xiu, Liu Xun-hong, Lan Cai-wu, Hou Ya, Ma Yang, Xu Li
Zhong Yao Cai. 2015 May;38(5):919-22.
To analyze the dynamic changes of nucleosides and nucleobases in Polygoni Multiflori Radix harvested in different periods.
UPLC-QTRAP-MS/MS method was applied for the analysis of nine kinds of nucleosides and nucleobases in Polygoni Multiflori Radix.
The content of uridine, adenine, guanosine and cytidine was higher in Polygoni Multiflori Radix harvested in different periods and assumed some difference. The trends of nucleosides and nucleobases from Polygoni Multiflori Radix according to the peak valley shape changed. The highest contents of them were in December.
The accumulation of nucleosides and nucleobases in Polygoni Multiflori Radix is closely related to its growth cycle. It is found to be basically the same as that obtained when the herb is collected during the conventional collecting time.
分析不同采收期何首乌中核苷和碱基的动态变化。
采用超高效液相色谱-四极杆飞行时间串联质谱法（UPLC-QTRAP-MS/MS）分析何首乌中的9种核苷和碱基。
不同采收期何首乌中尿苷、腺嘌呤、鸟苷和胞苷的含量较高，且存在一定差异。何首乌中核苷和碱基的峰谷形状变化趋势不同。它们的最高含量出现在12月。
何首乌中核苷和碱基的积累与其生长周期密切相关。发现其与传统采收期采收该药材时的情况基本相同。
