Zhao Meng-Jie, Gong Xiao-Hong, Dang Jue, Yuan An, Li Yan, Lou Lin, Liu Mei-Chen, Li Yun-Xia
The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources Co-founded by Sichuan Province and Ministry of Science and Technology of the People's Republic of China Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Zhongguo Zhong Yao Za Zhi. 2017 Apr;42(7):1344-1349. doi: 10.19540/j.cnki.cjcmm.20170121.030.
To study 48 h processing time of Polygoni Multiflori Radix on its contents and changes of chemical components. HPLC was used to determine the contents of various components in 22 Polygoni Multiflori Radix samples with different processing time, and then the fingerprint similarity analysis and clustering analysis were used for characteristics analysis. Results showed that the similarity was between 0.9-1.0, with good correlation between the samples. In the clustering analysis, the 22 Polygoni Multiflori Radix and processed Polygoni Multiflori Radix samples were classified into 4 types according to the composition changes. The results demonstrated that 4-5 h was the best processing time, providing references for quality control and further study of Polygoni Multiflori Radix.
研究何首乌48小时炮制时间对其化学成分含量及变化的影响。采用高效液相色谱法测定22个不同炮制时间的何首乌样品中各成分的含量，然后进行指纹图谱相似度分析和聚类分析以进行特征分析。结果表明，相似度在0.9 - 1.0之间，样品间相关性良好。在聚类分析中，22个何首乌及制何首乌样品根据成分变化分为4类。结果表明，4 - 5小时为最佳炮制时间，为何首乌的质量控制和进一步研究提供参考。
